{"id":"W2101137910","doi":"10.1016/j.ygeno.2010.02.008","title":"Genomic assessment of the evolution of the prion protein gene family in vertebrates","year":2010,"lang":"en","type":"article","venue":"Genomics","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Pseudogene; Biology; Gene; Genetics; Genome; Exon; PRNP; Phylogenetic tree; Locus (genetics); Phylogenetics; Homology (biology); Human genome; Gene family; Gene duplication; Evolutionary biology; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001682145,0.0001751744,0.0001633907,0.0005540287,0.000253495,0.0002386903,0.0001599861,0.0003106342,0.0007225609],"category_scores_gemma":[0.0002476578,0.0001015668,0.0001726861,0.0002864056,0.0002716768,0.0001200957,0.0001704832,0.0004196063,0.0001495632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003182064,"about_ca_system_score_gemma":0.0001673244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00141288,"about_ca_topic_score_gemma":0.002306333,"domain_scores_codex":[0.9999175,0.00001640754,0.00000580474,0.00002759479,0.00002022756,0.00001243683],"domain_scores_gemma":[0.9997541,0.00008964702,0.00005490962,0.00001826022,0.00002878775,0.00005412383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000131307,0.00001345536,0.003928387,0.00003599899,0.00001077603,0.0001806319,0.00006752271,0.0002435099,0.9921175,0.0002732417,0.00002190967,0.002975813],"study_design_scores_gemma":[0.00004434554,0.0007702272,0.7351099,0.00004820264,0.0001965418,0.003034977,0.0004793637,0.003978429,0.2474229,0.001261618,0.007628588,0.00002492779],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971831,0.0004944315,0.001193217,0.00005207124,0.000003274139,0.000007016396,0.0003006919,0.00001072577,0.0007552763],"genre_scores_gemma":[0.9961362,0.000415488,0.002095502,0.00005205389,0.000007747427,0.000005349705,0.0006064633,0.00001285908,0.0006682459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00141288,"threshold_uncertainty_score":0.002809286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004794303021926839,"score_gpt":0.2256215164025841,"score_spread":0.2208272133806573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}