{"id":"W2101191100","doi":"10.1073/pnas.0910023106","title":"Reconstitution of bacterial outer membrane TonB-dependent transporters in planar lipid bilayer membranes","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Purdue University","keywords":"Periplasmic space; Bacterial outer membrane; Biophysics; Lipid bilayer; Colicin; Biochemistry; Chemistry; Membrane; Transmembrane protein; Urea; Ion channel; Porin; Extracellular; Biology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003726196,0.0005252255,0.0005562686,0.0002146596,0.0002995509,0.0005624673,0.0007247035,0.0006809403,0.0006256108],"category_scores_gemma":[0.0004279917,0.0003566594,0.000518113,0.0003319311,0.000383974,0.0007050951,0.0006431111,0.0009904343,0.0006346309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000722119,"about_ca_system_score_gemma":0.0004071609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001673002,"about_ca_topic_score_gemma":0.0009275383,"domain_scores_codex":[0.9996431,0.00009223627,0.00005544728,0.00004883015,0.00009806615,0.00006238334],"domain_scores_gemma":[0.9997863,0.0000368677,0.00005525373,0.00003366957,0.00003702382,0.00005083144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001349986,0.00004578274,0.00008849632,0.00006515305,0.00001318867,0.00005014621,0.00004283845,0.000290554,0.998472,0.0003816835,0.00002525445,0.000389784],"study_design_scores_gemma":[0.0000556022,0.0002377083,0.0006489215,0.00001409076,0.00002469133,0.0001083082,0.00008043107,0.005743172,0.9907941,0.0001649042,0.002110482,0.00001747118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921396,0.0004900809,0.005722819,0.0002039897,0.00006364728,0.00009578271,0.0004760013,0.0001237181,0.0006844639],"genre_scores_gemma":[0.9858467,0.0009048646,0.01012822,0.00005324536,0.00001760967,0.0001060228,0.001200851,0.00008755198,0.001655003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001673002,"threshold_uncertainty_score":0.005239427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02109313794743607,"score_gpt":0.2612206198153713,"score_spread":0.2401274818679353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}