{"id":"W2101316199","doi":"10.1093/jb/mvg005","title":"Development and Characterization of a Novel Fusion Protein Composed of a Human IgG1 Heavy Chain Constant Region and a Single-Chain Fragment Variable Antibody against Venezuelan Equine Encephalitis Virus","year":2003,"lang":"en","type":"article","venue":"The Journal of Biochemistry","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Antibody; Recombinant DNA; Molecular biology; Epitope; Virology; Monoclonal antibody; Fusion protein; Biology; Immunogenicity; Immunoglobulin light chain; Antigen; Chemistry; Gene; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002600146,0.0003151039,0.0002229575,0.0002256062,0.0001724923,0.0003738309,0.0002553051,0.0003500296,0.0003627334],"category_scores_gemma":[0.0002289642,0.0001360886,0.000276091,0.0001562149,0.0001911721,0.0002298948,0.0001738945,0.0004520622,0.0002059186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005609615,"about_ca_system_score_gemma":0.0003217453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001758017,"about_ca_topic_score_gemma":0.001321167,"domain_scores_codex":[0.9998939,0.00001510244,0.000007422834,0.00002239297,0.00003442837,0.00002677456],"domain_scores_gemma":[0.9999316,0.0000132596,0.00001559635,0.000008473112,0.0000155715,0.00001551529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001862929,0.00002516662,0.0001876632,0.00001824538,0.000004025403,0.00004749332,0.00001555699,0.0000901914,0.9984509,0.00007163109,0.00001910555,0.001051328],"study_design_scores_gemma":[0.00003808286,0.0004325953,0.006051559,0.00001056642,0.00004380961,0.0008817209,0.0000576416,0.002220231,0.9819803,0.0000917491,0.008183074,0.000008780567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895048,0.001229007,0.008075755,0.0001909386,0.00002252229,0.00006946051,0.0002565041,0.00002960668,0.0006214346],"genre_scores_gemma":[0.982628,0.001045955,0.01182579,0.00007115306,0.00001432891,0.00005109292,0.002009308,0.00001490546,0.002339521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001758017,"threshold_uncertainty_score":0.004070044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690318527624768,"score_gpt":0.2490398349958372,"score_spread":0.2321366497195896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}