{"id":"W2101361999","doi":"10.1210/me.2004-0246","title":"c-Src Regulates Clathrin Adapter Protein 2 Interaction with β-Arrestin and the Angiotensin II Type 1 Receptor during Clathrin- Mediated Internalization","year":2004,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Clathrin; Internalization; Biology; Proto-oncogene tyrosine-protein kinase Src; Arrestin; Signal transducing adaptor protein; Cell biology; Adapter (computing); Receptor; Endocytosis; G protein-coupled receptor; Phosphorylation; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008671907,0.0002297799,0.0002154437,0.00005937477,0.0001548548,0.00003446814,0.0001551364,0.0001463571,0.00005819248],"category_scores_gemma":[0.00009256905,0.0001661491,0.00006471653,0.0001179989,0.0001815437,0.00001069264,0.0001911745,0.0001949299,0.000009858877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002409789,"about_ca_system_score_gemma":0.00003886138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008804847,"about_ca_topic_score_gemma":0.00003818918,"domain_scores_codex":[0.9987224,0.000120092,0.0002484405,0.0004476975,0.0001306619,0.0003307047],"domain_scores_gemma":[0.9993791,0.000009261395,0.0001377522,0.000269775,0.0001286403,0.00007544493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001151198,0.00002524363,0.00006354022,0.00001112523,0.0001019866,0.00003469873,0.0002217664,0.001437964,0.9946834,0.001845766,0.00002021019,0.0004030752],"study_design_scores_gemma":[0.0031474,0.0006645319,0.0001017938,0.00006528044,0.0000303157,0.0002045844,0.0001052211,0.0001671207,0.9917509,0.0003293603,0.003197212,0.0002362596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986178,0.001051686,0.01088932,0.0011921,0.0001326058,0.0004251373,0.00000259168,0.00003852888,0.00009005733],"genre_scores_gemma":[0.9972813,0.000141877,0.00179719,0.000381039,0.0001233976,0.00003600674,0.00007310703,0.00004333723,0.0001227455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01110333,"threshold_uncertainty_score":0.6775362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005403496396264049,"score_gpt":0.2064112307682178,"score_spread":0.2010077343719537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}