{"id":"W2101371049","doi":"10.1093/infdis/jiu285","title":"Mast Cells Impair Host Defense During Murine Streptococcus pneumoniae Pneumonia","year":2014,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Streptococcus pneumoniae; Pneumonia; Pneumococcal pneumonia; Tryptase; Immunology; Microbiology; Lung; Degranulation; Biology; Pathogen; Medicine; Mast cell; Antibiotics; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003547453,0.0006656858,0.0004500034,0.0002986285,0.0001638997,0.000237718,0.0002605178,0.0005909376,0.001289632],"category_scores_gemma":[0.00018103,0.0002269901,0.0002780615,0.000139829,0.0002925388,0.0002849689,0.0002876113,0.0009210211,0.0003850368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002407367,"about_ca_system_score_gemma":0.0002188538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002120842,"about_ca_topic_score_gemma":0.0003680364,"domain_scores_codex":[0.9996345,0.00008128938,0.00003714009,0.00004844364,0.00008306344,0.000115488],"domain_scores_gemma":[0.999761,0.00004662249,0.00006945658,0.00002599482,0.00001872807,0.00007813213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001303746,0.0001954659,0.0005529032,0.00007761466,0.00000750567,0.0001611828,0.00002639132,0.00006561065,0.9959347,0.00005704898,0.00004785902,0.001569971],"study_design_scores_gemma":[0.0002190189,0.006874053,0.01607247,0.00002452417,0.00005412988,0.000868999,0.00005679734,0.0007284822,0.9732783,0.00007629977,0.001738406,0.000008445844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996305,0.001961251,0.0006275213,0.0000567666,0.00003317769,0.00004846714,0.0002326154,0.00004810639,0.0006872251],"genre_scores_gemma":[0.9968668,0.0007833231,0.0006070878,0.00004715223,0.00001838967,0.00007536535,0.0003235496,0.00000939556,0.001268921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001289632,"threshold_uncertainty_score":0.004314244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003443810655919508,"score_gpt":0.1920912311961658,"score_spread":0.1886474205402462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}