{"id":"W2101445260","doi":"10.1113/jphysiol.2012.236893","title":"Bicarbonate‐dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu‐3","year":2012,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Bicarbonate; Secretion; Ion transporter; Cystic fibrosis transmembrane conductance regulator; Chemistry; Chloride channel; Epithelium; Amiloride; Forskolin; Cell culture; Transepithelial potential difference; Biophysics; Chloride; Sodium; Stimulation; Internal medicine; Endocrinology; Biochemistry; Biology; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002847103,0.0002507228,0.0004969368,0.00022314,0.0003657514,0.0006622605,0.0003716381,0.0004766408,0.001212686],"category_scores_gemma":[0.0004368419,0.000206855,0.0006022945,0.0004382778,0.0003017903,0.0002923721,0.0002645898,0.0009216772,0.000639171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007534458,"about_ca_system_score_gemma":0.0004535606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006480445,"about_ca_topic_score_gemma":0.005610771,"domain_scores_codex":[0.9995331,0.00007584028,0.00004476057,0.00007522137,0.0002004496,0.00007063201],"domain_scores_gemma":[0.9996959,0.0001019663,0.00003557665,0.00006815792,0.00006325099,0.0000350579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008163945,0.0000142045,0.0002283486,0.00002710454,0.000003540663,0.00004620977,0.00003196995,0.00004743503,0.9988864,0.00005084403,0.0000936209,0.000488654],"study_design_scores_gemma":[0.00006001482,0.0003724739,0.01306457,0.00001295992,0.00003173257,0.0004308804,0.0001507803,0.004169133,0.9759036,0.00009308735,0.005694037,0.0000166755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902379,0.002031727,0.002761849,0.0004366557,0.00009980727,0.00005889404,0.001675513,0.0001614464,0.002536335],"genre_scores_gemma":[0.992792,0.0006374549,0.002931138,0.0001736502,0.00001935651,0.00004627106,0.001896634,0.00002554558,0.001477952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006480445,"threshold_uncertainty_score":0.01288545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01454518033523912,"score_gpt":0.2936853039541245,"score_spread":0.2791401236188854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}