{"id":"W2101516244","doi":"10.1093/ndt/gfq749","title":"Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide","year":2011,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"","keywords":"Renal cortex; Internal medicine; Endocrinology; Streptozotocin; Diabetic nephropathy; Mesangial cell; Nitric oxide; Transforming growth factor; Sodium hydrosulfide; Medicine; Extracellular matrix; Western blot; Kidney; Biology; Diabetes mellitus; Chemistry; Biochemistry; Hydrogen sulfide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002365768,0.0002170133,0.0003042552,0.0001025731,0.00007305932,0.000008850323,0.0001504558,0.0005356752,0.00008943334],"category_scores_gemma":[0.00001780001,0.000227366,0.0001015513,0.000102059,0.0001378708,0.00001526359,0.00002424579,0.0001114685,0.00000679607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001396538,"about_ca_system_score_gemma":0.00003557191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007179439,"about_ca_topic_score_gemma":0.0004062399,"domain_scores_codex":[0.9983594,0.0003234763,0.0004405006,0.0005154373,0.0001301735,0.0002309966],"domain_scores_gemma":[0.9993474,0.00005544708,0.0001843839,0.0002738883,0.00007176759,0.00006715294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001127757,0.00007231241,0.007081488,0.00001492714,0.000219882,0.000005653619,0.0004396401,0.00003063507,0.9903078,0.0001108158,0.00005328673,0.0005357898],"study_design_scores_gemma":[0.001436276,0.0004068475,0.01659953,0.000005309199,0.0002893576,0.0000115562,0.000026399,0.0002951784,0.980091,0.000393641,0.000238277,0.0002066853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907703,0.001182254,0.007328849,0.00003414226,0.0001770718,0.0002392558,0.000205488,0.00002345343,0.0000391522],"genre_scores_gemma":[0.9939018,0.001211191,0.001331422,0.0001107474,0.0001667506,0.00003336826,0.003192913,0.00002512135,0.0000267104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01021687,"threshold_uncertainty_score":0.9271716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100254744753358,"score_gpt":0.2264397336625502,"score_spread":0.2164142591872144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}