{"id":"W2101524137","doi":"10.1056/nejmoa0901053","title":"Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections","year":2009,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":743,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Basilea Pharmaceutica; KWF Kankerbestrijding; Astellas Pharma; Wellcome Trust; National Institute of Allergy and Infectious Diseases; Pfizer; Medical Research Council; Abbott Laboratories","keywords":"Chronic mucocutaneous candidiasis; Candida albicans; Phagocytosis; Immunology; Medicine; Immune system; Tumor necrosis factor alpha; Mucocutaneous zone; Microbiology; Biology; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003669672,0.00008386819,0.0001837648,0.00002507814,0.0001409025,0.0000181406,0.00009462911,0.00004169295,0.0003277104],"category_scores_gemma":[0.00009194735,0.00002676053,0.00003501853,0.0001284381,0.00003331921,0.00006081125,0.000007619178,0.0001842929,0.00000202927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008436202,"about_ca_system_score_gemma":0.000008909851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002582009,"about_ca_topic_score_gemma":0.0002920883,"domain_scores_codex":[0.9993089,0.00003812211,0.0002480451,0.00008005038,0.000179604,0.0001452425],"domain_scores_gemma":[0.999414,0.0001701543,0.0001448174,0.00002129873,0.00004870149,0.0002010895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00004534862,0.0000628683,0.006363445,0.000002155891,0.000009272592,0.0001877413,0.0002327361,0.000008273102,0.3236137,0.0004188944,0.003055751,0.6659998],"study_design_scores_gemma":[0.01611147,0.02986063,0.5955992,0.0004507542,0.000304797,0.04916346,0.0006572226,0.00006552201,0.002904432,0.02522347,0.2789996,0.0006595105],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910104,0.001232933,0.00001269358,0.004680671,0.000195828,0.00003476398,0.000001975044,0.0000105873,0.002820153],"genre_scores_gemma":[0.9966956,0.000304534,0.00002604106,0.0004302073,0.002182175,6.516175e-8,0.000001722537,3.435295e-7,0.0003593141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6653403,"threshold_uncertainty_score":0.35882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01519584617230348,"score_gpt":0.2336749942784631,"score_spread":0.2184791481061596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}