{"id":"W2101569447","doi":"10.1126/science.1239278","title":"Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds","year":2013,"lang":"en","type":"article","venue":"Science","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1389,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University; Microsoft Research","keywords":"Reprogramming; Induced pluripotent stem cell; Somatic cell; Embryonic stem cell; Biology; Stem cell; Cell biology; Regenerative medicine; Germline; Cell potency; Cellular differentiation; Induced stem cells; Epigenetics; Genetics; Cell; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003248927,0.0006060532,0.0003797048,0.0004729115,0.000174165,0.0002737397,0.0001847365,0.0002993462,0.001838402],"category_scores_gemma":[0.0002069512,0.0001665891,0.0003526976,0.0002733287,0.0002320317,0.0002105686,0.0002821686,0.0005329511,0.0006642112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001574783,"about_ca_system_score_gemma":0.0002755199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000112307,"about_ca_topic_score_gemma":0.000276194,"domain_scores_codex":[0.9998087,0.00003654778,0.00003088025,0.00002685495,0.00007531866,0.00002164406],"domain_scores_gemma":[0.9998851,0.00003351981,0.00003128633,0.00001544857,0.00001514944,0.00001960504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002559983,0.000009838359,0.00006809911,0.00005427693,0.000007049427,0.00002792991,0.000004602285,0.00007912249,0.997085,0.0001647919,0.00005118231,0.00242258],"study_design_scores_gemma":[0.00001436343,0.0002196293,0.0003618534,0.000004967875,0.00001869646,0.00009030725,0.000003420021,0.0001394507,0.996192,0.00005012024,0.002901742,0.00000360767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8720683,0.01323476,0.09155976,0.0006701898,0.0003542566,0.001118771,0.003535603,0.001207505,0.01625079],"genre_scores_gemma":[0.9494739,0.007583999,0.03377123,0.0002676108,0.00006279601,0.0005085117,0.002222721,0.0001075838,0.006001594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838402,"threshold_uncertainty_score":0.006150126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01648234363146699,"score_gpt":0.2381447678658764,"score_spread":0.2216624242344093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}