{"id":"W2101584970","doi":"10.1002/jcp.21243","title":"Cyclin D1/cdk4 can interact with E2F4/DP1 and disrupts its DNA‐binding capacity","year":2007,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cyclin D1; E2F; Cyclin A; Cyclin D; Cyclin A2; Biology; Cell biology; Molecular biology; Cyclin-dependent kinase complex; Cyclin; Cyclin E; Cell cycle; Cancer research; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004788786,0.0002193448,0.0006034211,0.0002572452,0.00007103235,0.0000127032,0.0001143319,0.0001754086,0.00007233315],"category_scores_gemma":[0.0001266066,0.0001633827,0.0001521517,0.0001837634,0.0001486705,0.00009251836,0.00004538943,0.0008027926,0.00001098942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001732997,"about_ca_system_score_gemma":0.0001475589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000247814,"about_ca_topic_score_gemma":0.00005652006,"domain_scores_codex":[0.9984665,0.00008848459,0.0005427608,0.0002311014,0.0002739291,0.0003972485],"domain_scores_gemma":[0.9986131,0.0001125053,0.0005185357,0.0002136616,0.0002278306,0.0003143285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000934888,0.0001280754,0.000834361,0.00006938253,0.0002327007,0.0008691502,0.0005170025,0.00002278648,0.9950055,0.00005068864,0.0001509318,0.001184569],"study_design_scores_gemma":[0.004675712,0.002831196,0.03794167,0.0005901089,0.0003955564,0.004621034,0.0003916472,0.0001384179,0.9434665,0.0001903078,0.004427371,0.0003304777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964756,0.0006131071,0.001275399,0.0003853116,0.0005881715,0.0001729761,0.000005967373,0.00001436523,0.0004691355],"genre_scores_gemma":[0.9982952,0.0001075109,0.000594122,0.0002879626,0.000519927,0.000001114062,0.000009556123,0.00003764383,0.0001469688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05153897,"threshold_uncertainty_score":0.6662552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515387417873801,"score_gpt":0.2538384103785976,"score_spread":0.2386845361998596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}