{"id":"W2101584970","doi":"10.1002/jcp.21243","title":"Cyclin D1/cdk4 can interact with E2F4/DP1 and disrupts its DNA‐binding capacity","year":2007,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cyclin D1; E2F; Cyclin A; Cyclin D; Cyclin A2; Biology; Cell biology; Molecular biology; Cyclin-dependent kinase complex; Cyclin; Cyclin E; Cell cycle; Cancer research; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001519774,0.0004919835,0.0002486963,0.0003334024,0.0002889101,0.0003390235,0.000410588,0.0003328273,0.001512063],"category_scores_gemma":[0.0002016117,0.000205197,0.0003372023,0.0002127275,0.0002709859,0.0001556823,0.0003072251,0.0004423481,0.0005366298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009221784,"about_ca_system_score_gemma":0.0003763913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002849925,"about_ca_topic_score_gemma":0.002163568,"domain_scores_codex":[0.9998404,0.00002081497,0.00001242963,0.00003273381,0.00004357564,0.00004999365],"domain_scores_gemma":[0.9999244,0.00001723461,0.00002327783,0.00001210805,0.000007634287,0.00001536494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007721203,0.00003383218,0.0006893831,0.00005856792,0.00001387858,0.00009165029,0.000006195921,0.0001729105,0.9960651,0.0003047034,0.000100949,0.00238563],"study_design_scores_gemma":[0.000009441676,0.00005753371,0.003068861,0.000004204351,0.00001295769,0.0003108271,0.000008596063,0.0008501881,0.9869013,0.00005633262,0.008714919,0.000004773532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983331,0.004428132,0.007688973,0.0002377711,0.00009143606,0.00005356351,0.0005451392,0.0001044756,0.003519479],"genre_scores_gemma":[0.9895068,0.001546815,0.003642155,0.00006590642,0.00001109855,0.00004390683,0.001059379,0.00002552479,0.004098324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002849925,"threshold_uncertainty_score":0.00669086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515387417873801,"score_gpt":0.2538384103785976,"score_spread":0.2386845361998596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}