{"id":"W2101596455","doi":"10.1139/y10-053","title":"Combination therapy of zibotentan with cisplatinum and paclitaxel is an effective regimen for epithelial ovarian cancerThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Paclitaxel; Ovarian cancer; Medicine; Taxane; Combination therapy; Cancer research; Angiogenesis; Pharmacology; Cisplatin; Cell growth; Cancer; Oncology; Chemotherapy; Internal medicine; Breast cancer; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001016915,0.0002079184,0.0004995295,0.0004523635,0.0001685725,0.0002242968,0.000214455,0.000201978,0.001048241],"category_scores_gemma":[0.00008475284,0.00009178263,0.0002599836,0.0003757825,0.0001115145,0.000213099,0.0002247358,0.0004757142,0.0001983194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002869181,"about_ca_system_score_gemma":0.0002433175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002916408,"about_ca_topic_score_gemma":0.001308635,"domain_scores_codex":[0.9999324,0.0000110369,0.000005284769,0.0000138354,0.00002510234,0.00001228139],"domain_scores_gemma":[0.9999702,0.000005415493,0.000007438161,0.000003514205,0.000003595975,0.000009952524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003679486,0.001601104,0.004929829,0.001085877,0.0003566514,0.0006077964,0.00007963268,0.001217642,0.6840222,0.0005556737,0.00260809,0.2992561],"study_design_scores_gemma":[0.002945131,0.04274388,0.1112326,0.0002108548,0.001057313,0.005714547,0.0001746773,0.007415654,0.6569719,0.0006651347,0.170786,0.00008236893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9169109,0.07107947,0.004283532,0.0007171051,0.0004669642,0.0004854613,0.0002937539,0.0001707409,0.005592048],"genre_scores_gemma":[0.975685,0.01834793,0.002808825,0.0002273003,0.0001018054,0.0001408848,0.0003343099,0.00001603704,0.002337834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001048241,"threshold_uncertainty_score":0.00350672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01936440539489517,"score_gpt":0.3191649560765711,"score_spread":0.299800550681676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}