{"id":"W2101666731","doi":"10.1136/jclinpath-2013-201471","title":"Molecular biology of normal melanocytes and melanoma cells","year":2013,"lang":"en","type":"review","venue":"Journal of Clinical Pathology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Melanoma; Melanocyte; Cancer research; Malignant transformation; Skin cancer; Biology; Population; Cell; Cancer; Cell growth; Medicine; Immunology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001499768,0.0003861116,0.003003387,0.0001743758,0.00002474074,0.00001002092,0.0005258087,0.001473218,0.00004522946],"category_scores_gemma":[0.000762341,0.0002735332,0.00113414,0.00007739304,0.000455169,0.000005242239,0.0003129937,0.0006826736,0.00001830314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006192494,"about_ca_system_score_gemma":0.0004053639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002325906,"about_ca_topic_score_gemma":0.000001220918,"domain_scores_codex":[0.995249,0.001100369,0.002791702,0.0004152595,0.0001273289,0.0003163389],"domain_scores_gemma":[0.9958404,0.0003480451,0.002838827,0.0004616239,0.0002703113,0.0002408009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008933757,0.0002222035,0.0003618431,0.002197794,0.000671156,0.0003751897,0.00001186209,8.108166e-7,0.01848635,0.0004675449,0.001384754,0.9757311],"study_design_scores_gemma":[0.0007930776,0.003884407,0.00004411234,0.0005881048,0.0007152215,0.001757647,0.000007726282,7.753088e-7,0.004492478,0.0002660974,0.987138,0.0003123025],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03443592,0.9628257,0.0006308215,0.00001933463,0.001194824,0.0002496417,0.00005405754,0.000002832134,0.0005869168],"genre_scores_gemma":[0.002254723,0.993874,0.002729999,0.00009495483,0.0008246691,0.000008750597,0.00004653041,0.0000439131,0.0001224732],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9857533,"threshold_uncertainty_score":0.9999717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0628149022130208,"score_gpt":0.400415545993399,"score_spread":0.3376006437803782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}