{"id":"W2101680466","doi":"10.1093/nar/gkt704","title":"Model of the Mediator middle module based on protein cross-linking","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome British Columbia; University of Victoria","funders":"","keywords":"Biology; Tetramer; Mediator; Protein subunit; Computational biology; Transcription (linguistics); RNA polymerase II; Homology (biology); Cell biology; Genetics; Biochemistry; Amino acid; Gene; Gene expression; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007445335,0.0005110822,0.0003316404,0.0002942109,0.0005502098,0.0008762797,0.00105914,0.0009375549,0.01088823],"category_scores_gemma":[0.0001127135,0.0003320834,0.0007114666,0.0002753602,0.0004569649,0.0007687027,0.0005496618,0.0005431375,0.002105238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007170676,"about_ca_system_score_gemma":0.0005981954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002322823,"about_ca_topic_score_gemma":0.0010828,"domain_scores_codex":[0.9999527,0.000008471199,0.000002384499,0.0000122767,0.00001411002,0.00001008343],"domain_scores_gemma":[0.9999611,0.000006899822,0.000007284718,0.00000508942,0.000005756216,0.00001389857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006535833,0.0001267104,0.001442993,0.0004267803,0.0000978428,0.002098662,0.0004675536,0.5185413,0.2274774,0.2272178,0.003616123,0.01783319],"study_design_scores_gemma":[0.0002393908,0.0002717918,0.001494101,0.0000566167,0.00007283517,0.0007764878,0.0001552805,0.8666326,0.02601566,0.05502805,0.04917086,0.00008621134],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4652101,0.002391953,0.4453117,0.00140782,0.0004177466,0.0002453722,0.002874074,0.003764403,0.07837677],"genre_scores_gemma":[0.8906763,0.001207085,0.09123329,0.0001137464,0.00003010256,0.0002876824,0.001466008,0.0002099215,0.01477587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01088823,"threshold_uncertainty_score":0.0364247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06030399001870307,"score_gpt":0.3139178745895709,"score_spread":0.2536138845708679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}