{"id":"W2101683986","doi":"10.4161/23723548.2014.965638","title":"Necroptosis: Fifty shades of RIPKs","year":2014,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Necroptosis; RIPK1; Programmed cell death; Cell biology; Apoptosis; Biology; Kinase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000365008,0.0001957298,0.0002936636,0.00007234262,0.00006389924,0.00001063066,0.0002407009,0.0003882484,0.00007647282],"category_scores_gemma":[0.00007486117,0.0001884998,0.0001987646,0.0001044402,0.0001237263,0.000002847734,0.0001441715,0.0001059438,0.00001979381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002106633,"about_ca_system_score_gemma":0.00007534863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002594142,"about_ca_topic_score_gemma":0.00001273835,"domain_scores_codex":[0.9985802,0.0002133333,0.0003330897,0.000413436,0.0001643069,0.0002956033],"domain_scores_gemma":[0.9990847,0.00001536304,0.0001783863,0.000507728,0.0001110897,0.0001026927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005081596,0.0001115422,0.000146026,0.00002621081,0.00005493292,0.000008755427,0.00003439547,0.0003005616,0.9815166,0.002620334,0.0003047136,0.01482512],"study_design_scores_gemma":[0.0006307929,0.0007771444,0.0002771366,0.000009032524,0.00004684688,0.00001341604,0.00002521249,0.0005216055,0.8282244,0.0007272892,0.1685653,0.0001818666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8389871,0.001349513,0.1523595,0.0002018543,0.0002879133,0.0002172968,0.000004817277,0.00001969782,0.006572342],"genre_scores_gemma":[0.9932207,0.0001054159,0.00533335,0.0003594895,0.0001567067,0.0000218626,0.0001616847,0.00003718153,0.0006035647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1682605,"threshold_uncertainty_score":0.7686798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005088605210911216,"score_gpt":0.232457875364851,"score_spread":0.2273692701539397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}