{"id":"W2101683986","doi":"10.4161/23723548.2014.965638","title":"Necroptosis: Fifty shades of RIPKs","year":2014,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Necroptosis; RIPK1; Programmed cell death; Cell biology; Apoptosis; Biology; Kinase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001840156,0.000533512,0.001028938,0.001165677,0.001318578,0.004157641,0.0007166459,0.001533238,0.004092617],"category_scores_gemma":[0.00132992,0.0004176961,0.0007289047,0.0008873414,0.003710401,0.006237019,0.003172363,0.003587279,0.00150833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009640148,"about_ca_system_score_gemma":0.0004194553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001535788,"about_ca_topic_score_gemma":0.0002796497,"domain_scores_codex":[0.9985585,0.000268961,0.00008906102,0.0002891205,0.0005306326,0.0002637153],"domain_scores_gemma":[0.9992487,0.0001982877,0.00009198979,0.0001729726,0.0001199396,0.00016813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002168176,0.0001679853,0.004761994,0.002430769,0.0002951905,0.002268498,0.003580224,0.001039544,0.2650037,0.277633,0.05034269,0.3903082],"study_design_scores_gemma":[0.000167982,0.0006591976,0.01713032,0.001151116,0.0002219442,0.009584763,0.004227058,0.001197649,0.07524398,0.2563498,0.6337633,0.0003030515],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1434608,0.6288173,0.03440531,0.08362766,0.00757665,0.00006202081,0.0004850601,0.001811425,0.09975374],"genre_scores_gemma":[0.7163743,0.2031854,0.01452945,0.02210049,0.00441547,0.00008792683,0.0003693295,0.000427921,0.03850978],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004157641,"threshold_uncertainty_score":0.01369113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005088605210911216,"score_gpt":0.232457875364851,"score_spread":0.2273692701539397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}