{"id":"W2101701484","doi":"10.1002/cncr.24362","title":"Carboplatin‐based primary chemotherapy for infants and young children with CNS tumors","year":2009,"lang":"en","type":"article","venue":"Cancer","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute","keywords":"Carboplatin; Medicine; Medulloblastoma; Etoposide; Ototoxicity; Chemotherapy; Ependymoma; Internal medicine; Oncology; Radiation therapy; Atypical teratoid rhabdoid tumor; Chemotherapy regimen; Cyclophosphamide; Regimen; Cisplatin; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001506273,0.0002101454,0.0003325307,0.0001359285,0.0002333329,0.0001425081,0.0001568434,0.0001935591,0.0004855333],"category_scores_gemma":[0.000548433,0.00006062816,0.0002058005,0.000178702,0.0001481831,0.00008731413,0.0001496053,0.0002392925,0.0001110598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003968879,"about_ca_system_score_gemma":0.0006052681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002055052,"about_ca_topic_score_gemma":0.004561458,"domain_scores_codex":[0.9999136,0.00002682953,0.00001095052,0.000008969292,0.00001409145,0.00002560114],"domain_scores_gemma":[0.9998201,0.00004527541,0.00005851647,0.000006468914,0.00001785622,0.00005188778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.003843151,0.000349507,0.7424845,0.001076201,0.000221574,0.02182441,0.0006756056,0.001422822,0.02127439,0.0002342787,0.003820032,0.2027735],"study_design_scores_gemma":[0.0006258675,0.008159731,0.8494879,0.0003359864,0.0004157214,0.0948745,0.0006779712,0.00149207,0.01853496,0.0001656331,0.02520775,0.00002198214],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869325,0.01124119,0.0005205678,0.000116582,0.00002308478,0.00004595254,0.00009857583,0.00002792121,0.0009936381],"genre_scores_gemma":[0.9946973,0.003792315,0.000901712,0.00007835042,0.00001726584,0.00005194767,0.0002388411,0.000004967006,0.0002171616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002055052,"threshold_uncertainty_score":0.004086196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005552028367106454,"score_gpt":0.2451631438212096,"score_spread":0.2396111154541032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}