{"id":"W2101701484","doi":"10.1002/cncr.24362","title":"Carboplatin‐based primary chemotherapy for infants and young children with CNS tumors","year":2009,"lang":"en","type":"article","venue":"Cancer","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute","keywords":"Carboplatin; Medicine; Medulloblastoma; Etoposide; Ototoxicity; Chemotherapy; Ependymoma; Internal medicine; Oncology; Radiation therapy; Atypical teratoid rhabdoid tumor; Chemotherapy regimen; Cyclophosphamide; Regimen; Cisplatin; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003737398,0.0001092132,0.0001069712,0.00001320111,0.00004938168,0.00001411851,0.00005749658,0.00005948326,0.000007992837],"category_scores_gemma":[0.000004176316,0.00009010091,0.0000311827,0.0000332676,0.00003354616,0.000002156722,0.000006065315,0.00003582622,1.735042e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000188683,"about_ca_system_score_gemma":0.0001167796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003331595,"about_ca_topic_score_gemma":0.00003059958,"domain_scores_codex":[0.9994748,0.00000551307,0.00008279642,0.0002269026,0.00006200011,0.0001480168],"domain_scores_gemma":[0.9997192,0.000002336216,0.00004426016,0.000149489,0.00003888074,0.00004583314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001043921,0.00009084093,0.08536128,0.00006825137,0.0001869284,0.00000121698,0.0001987174,0.001881854,0.7584575,0.00002238228,0.009484277,0.1432028],"study_design_scores_gemma":[0.008412008,0.001321639,0.5426718,0.0001718888,0.00009202351,0.00003668273,0.00002363392,0.002860802,0.4346267,0.0001271479,0.008753068,0.0009026333],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953691,0.001970849,0.001640551,0.000238189,0.00003715502,0.0002243542,0.00003589855,0.0000143926,0.0004695535],"genre_scores_gemma":[0.9954001,0.0001785327,0.00147756,0.002329846,0.0002296558,0.00004200371,0.00007745241,0.00001792728,0.0002469329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4573105,"threshold_uncertainty_score":0.3674209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005552028367106454,"score_gpt":0.2451631438212096,"score_spread":0.2396111154541032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}