{"id":"W2101787639","doi":"10.3389/fninf.2012.00003","title":"Models of the aging brain structure and individual decline","year":2012,"lang":"en","type":"article","venue":"Frontiers in Neuroinformatics","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Mental Health; National Institute on Aging; University of California, San Diego; Genentech; National Institutes of Health; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, Los Angeles; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; Alzheimer's Association; Amorfix Life Sciences; National Center for Research Resources; F. Hoffmann-La Roche; Medpace; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Novartis Pharmaceuticals Corporation; Synarc; Dana Foundation; Bayer HealthCare; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Foundation for the National Institutes of Health","keywords":"Brain aging; Aging brain; Psychology; Cognitive psychology; Computer science; Neuroscience; Cognition","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002359567,0.0001120759,0.0001604842,0.0001062334,0.0001125118,0.0000227929,0.0002425753,0.00003963124,0.000001697685],"category_scores_gemma":[0.003177342,0.00008233485,0.00003229655,0.0002916455,0.0001879391,0.0006710009,0.0003999099,0.0002232618,4.432707e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000189584,"about_ca_system_score_gemma":0.00002059612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002399709,"about_ca_topic_score_gemma":0.000003166692,"domain_scores_codex":[0.9989963,0.00007661238,0.0002623156,0.00009827836,0.0003269286,0.0002395707],"domain_scores_gemma":[0.9986345,0.0009620037,0.0001375001,0.000211194,0.00001415467,0.00004063679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001083704,0.0002301025,0.7112671,0.0005860994,0.00006642702,0.000004493896,0.0420859,0.03027427,0.007902129,0.02510858,0.1546819,0.02768463],"study_design_scores_gemma":[0.003599096,0.0002266196,0.3645323,0.0002168409,0.0001011822,0.0002152091,0.004598601,0.4167212,0.1006973,0.08283716,0.02509899,0.001155585],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907603,0.0001809079,0.002841787,0.00340295,0.001569933,0.0002529065,0.00006482864,0.00002432891,0.0009021138],"genre_scores_gemma":[0.991133,0.00002853895,0.003033193,0.005718536,0.00003981034,0.000002349973,7.238102e-7,0.000009058104,0.00003474939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3864469,"threshold_uncertainty_score":0.3803804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03410118461675723,"score_gpt":0.2420958502072172,"score_spread":0.20799466559046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}