{"id":"W2101885674","doi":"10.1016/j.molcel.2010.05.017","title":"Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition","year":2010,"lang":"en","type":"article","venue":"Molecular Cell","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":401,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Biology; PI3K/AKT/mTOR pathway; Discovery and development of mTOR inhibitors; Sirolimus; Computational biology; Cell biology; Signal transduction; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190174211634484,"score_gpt":0.2646194959987981,"score_spread":0.2527177538824533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}