{"id":"W2101919376","doi":"10.1126/stke.2002.127.re3","title":"ADAP-ting TCR Signaling to Integrins","year":2002,"lang":"en","type":"review","venue":"Science s STKE","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"T-cell receptor; Signal transducing adaptor protein; Cell biology; FYN; Integrin; Biology; Signal transduction; Immunological synapse; T cell; Proto-oncogene tyrosine-protein kinase Src; Receptor; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009896924,0.0005525472,0.001432651,0.0007449472,0.0008107633,0.00009050925,0.002005847,0.0006079845,0.001876319],"category_scores_gemma":[0.00035507,0.0004165368,0.000375702,0.001544484,0.001165826,0.0001638655,0.0007321241,0.001224353,0.013052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002230134,"about_ca_system_score_gemma":0.000532427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007593941,"about_ca_topic_score_gemma":0.00001356372,"domain_scores_codex":[0.9964994,0.000243334,0.0007526076,0.001124463,0.0001136736,0.001266579],"domain_scores_gemma":[0.9983984,0.0002534495,0.0003418731,0.0007836867,0.0001380744,0.00008453787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003243369,0.00006727814,0.000001350951,0.000431874,0.00006795234,0.00001354181,0.0002376806,0.000001112507,0.1045159,0.0005388237,0.001455348,0.8926659],"study_design_scores_gemma":[0.0001429161,0.0001613155,4.692364e-7,0.002490872,0.0001449955,0.0002270709,0.0001395124,6.583494e-7,0.004105152,0.00002924061,0.9920576,0.0005002617],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002462518,0.9867415,0.00007681867,0.00005565783,0.003164074,0.0005618897,0.0000327573,0.0001539422,0.00896707],"genre_scores_gemma":[0.001634691,0.9793318,0.0003358574,0.0001610029,0.0001301488,0.00007295713,0.00004224394,0.00004664675,0.01824464],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906022,"threshold_uncertainty_score":0.9998286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05514833850446561,"score_gpt":0.3043137067022297,"score_spread":0.2491653681977641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}