{"id":"W2101940205","doi":"10.1016/j.jalz.2011.09.065","title":"P4‐320: LRP10, a new regulator of APP trafficking and processing","year":2011,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Endosome; Amyloid precursor protein; Cell biology; Retromer; Alpha secretase; Golgi apparatus; Transport protein; Amyloid precursor protein secretase; Subcellular localization; Mutant; Biology; Intracellular; Alzheimer's disease; Biochemistry; Cytoplasm; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258117,0.0009870591,0.0002836921,0.0002758469,0.000270827,0.0004674109,0.0004252207,0.0004327249,0.002566291],"category_scores_gemma":[0.0001002729,0.0001390268,0.00019891,0.000202412,0.0003512776,0.0002210983,0.0003308774,0.0004808783,0.002287644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004746312,"about_ca_system_score_gemma":0.0003314789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007093188,"about_ca_topic_score_gemma":0.0002925363,"domain_scores_codex":[0.9998996,0.00001043876,0.00000632478,0.0000314028,0.00003326287,0.0000189244],"domain_scores_gemma":[0.9999588,0.000003442264,0.00001240699,0.00000251187,0.000008693936,0.00001418603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003699607,0.00006313257,0.000894064,0.0002166726,0.00001227016,0.001458221,0.00002954966,0.000140274,0.9763752,0.0005251346,0.002569377,0.0173462],"study_design_scores_gemma":[0.0001289516,0.0008186388,0.0178189,0.00003628926,0.00006352645,0.01196874,0.00007121346,0.001564601,0.8342882,0.0006663412,0.1325471,0.00002747105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9072567,0.04077379,0.01640231,0.001130398,0.000622678,0.0003679753,0.004185427,0.002410515,0.02685019],"genre_scores_gemma":[0.9098359,0.01653093,0.006431884,0.0004778482,0.0003256902,0.0004774778,0.007900201,0.0001323264,0.05788763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002566291,"threshold_uncertainty_score":0.008585036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05398901905141142,"score_gpt":0.3024527789730858,"score_spread":0.2484637599216744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}