{"id":"W2101980112","doi":"10.2337/db14-1151","title":"Reactivated CD4+Tm Cells of T1D Patients and Siblings Display an Exaggerated Effector Phenotype With Heightened Sensitivity to Activation-Induced Cell Death","year":2014,"lang":"en","type":"article","venue":"Diabetes","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Effector; Phenotype; Sensitivity (control systems); Medicine; Cell biology; Biology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017244,0.0004504639,0.0003049597,0.0006133789,0.0003612922,0.0003215233,0.000200639,0.0003221222,0.002409142],"category_scores_gemma":[0.0004953187,0.0001836252,0.0001851752,0.0002820964,0.000235595,0.0001807342,0.0003369432,0.0003288491,0.0003923063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001995451,"about_ca_system_score_gemma":0.0001150282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007917307,"about_ca_topic_score_gemma":0.0006521387,"domain_scores_codex":[0.9998131,0.00002448858,0.00002693646,0.00007751935,0.00002885875,0.00002910146],"domain_scores_gemma":[0.9997502,0.00004179758,0.00008328065,0.00003400563,0.0000268469,0.00006384173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001873597,0.0002300565,0.4813504,0.0001548408,0.0001117429,0.009560151,0.001572256,0.0002421326,0.486531,0.000158783,0.0003905121,0.01782443],"study_design_scores_gemma":[0.00004931473,0.001567108,0.9360151,0.00001616696,0.00008300275,0.02959781,0.0006804451,0.0003456892,0.03045432,0.0001353539,0.001036846,0.00001887025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994276,0.00009666471,0.00009171445,0.000007597353,0.000002152255,0.000006242247,0.0001501684,0.000006237765,0.0002116234],"genre_scores_gemma":[0.999155,0.00008058474,0.0001765933,0.00001690221,0.000006740723,0.00001118518,0.0002843975,0.000005710421,0.0002628785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002409142,"threshold_uncertainty_score":0.008059323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00667627571628668,"score_gpt":0.1948690510593831,"score_spread":0.1881927753430964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}