{"id":"W2101994325","doi":"10.2337/diabetes.50.8.1901","title":"Defective Insulin-Induced GLUT4 Translocation in Skeletal Muscle of High Fat–Fed Rats Is Associated With Alterations in Both Akt/Protein Kinase B and Atypical Protein Kinase C (ζ/λ) Activities","year":2001,"lang":"en","type":"article","venue":"Diabetes","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Medical Research Council; Medical Research Council Canada; Canadian Diabetes Association","keywords":"GLUT4; Protein kinase B; Skeletal muscle; Internal medicine; Chromosomal translocation; Endocrinology; Protein kinase A; Insulin; Kinase; Biology; Glucose uptake; Medicine; Cell biology; Phosphorylation; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002299647,0.001043492,0.0004176348,0.000886858,0.000283826,0.0002924783,0.0002894507,0.0004126258,0.002481753],"category_scores_gemma":[0.0001628069,0.0005248932,0.0004781724,0.0003518829,0.0005402255,0.0004167332,0.0004261189,0.0009328648,0.0004835991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003638513,"about_ca_system_score_gemma":0.0002790882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009704442,"about_ca_topic_score_gemma":0.00112821,"domain_scores_codex":[0.9997955,0.0000242937,0.00002359329,0.0000547735,0.00004980245,0.00005200217],"domain_scores_gemma":[0.9996387,0.00002579511,0.0001184136,0.00004305801,0.00003113354,0.0001429295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007120677,0.00006154072,0.000495375,0.00002704312,0.0000104929,0.00006027167,0.00001315591,0.00001348128,0.9980581,0.000026123,0.00001026528,0.0005120676],"study_design_scores_gemma":[0.0001363618,0.002817718,0.06002538,0.00001666637,0.0001023661,0.0007289897,0.000157675,0.0006200089,0.9344147,0.0001219118,0.0008379301,0.00002040263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983193,0.0002994259,0.0008479346,0.00003590907,0.00001634461,0.00001454494,0.0001448338,0.00005281836,0.0002688879],"genre_scores_gemma":[0.993154,0.0006989046,0.002099812,0.00006451639,0.00001502567,0.00008330541,0.0007279229,0.0000478214,0.003108611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002481753,"threshold_uncertainty_score":0.008302331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008493511999067258,"score_gpt":0.2233889952914726,"score_spread":0.2148954832924054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}