{"id":"W2101994325","doi":"10.2337/diabetes.50.8.1901","title":"Defective Insulin-Induced GLUT4 Translocation in Skeletal Muscle of High Fat–Fed Rats Is Associated With Alterations in Both Akt/Protein Kinase B and Atypical Protein Kinase C (ζ/λ) Activities","year":2001,"lang":"en","type":"article","venue":"Diabetes","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Medical Research Council; Medical Research Council Canada; Canadian Diabetes Association","keywords":"GLUT4; Protein kinase B; Skeletal muscle; Internal medicine; Chromosomal translocation; Endocrinology; Protein kinase A; Insulin; Kinase; Biology; Glucose uptake; Medicine; Cell biology; Phosphorylation; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001878469,0.0002066382,0.0003202212,0.0001139957,0.00005447084,0.0000264538,0.00008849696,0.0001896974,0.00002664376],"category_scores_gemma":[0.0001099276,0.0001960125,0.000052035,0.0002731774,0.0001079273,0.00002755683,0.00002494773,0.000148585,0.000001193743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003694972,"about_ca_system_score_gemma":0.00009162289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000154699,"about_ca_topic_score_gemma":0.0009784311,"domain_scores_codex":[0.9986969,0.000185365,0.0002724103,0.0003822211,0.0001458927,0.000317271],"domain_scores_gemma":[0.999512,0.00002724213,0.0001192932,0.0002012737,0.00007255931,0.00006761152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002236532,0.0003094146,0.004510922,0.00003874231,0.00005979127,0.000003606995,0.0005055145,0.0000200049,0.9630806,0.0001024258,0.00001198679,0.03113333],"study_design_scores_gemma":[0.002072451,0.000575955,0.05330471,0.0001732844,0.00002088125,2.106629e-7,0.000182858,0.0001274738,0.9427094,0.0002983105,0.000266203,0.0002682855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907307,0.008378688,0.00003337814,0.00004636075,0.00002780151,0.0006646496,0.00006177623,0.00001115591,0.00004549295],"genre_scores_gemma":[0.9988493,0.0003587189,0.0001157544,0.0000995797,0.00005353328,0.0003358685,0.0001250051,0.0000253592,0.00003682559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04879379,"threshold_uncertainty_score":0.7993156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008493511999067258,"score_gpt":0.2233889952914726,"score_spread":0.2148954832924054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}