{"id":"W2102014108","doi":"10.1073/pnas.0508048103","title":"Crystal structure of a core spliceosomal protein interface","year":2006,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Spliceosome; snRNP; RNA splicing; Intron; Small nuclear ribonucleoprotein; Small nuclear RNA; Minor spliceosome; RNA; Cell biology; Biology; Ribonucleoprotein; Biophysics; Chemistry; Biochemistry; Non-coding RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002545421,0.00005506885,0.00007820616,0.00005090261,0.00006071612,0.000007681034,0.000466918,0.00006611457,0.000005355051],"category_scores_gemma":[0.0001714709,0.00003605704,0.00004711083,0.0002162239,0.0005034001,0.00001258781,0.0001367916,0.0000756357,8.539819e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000618627,"about_ca_system_score_gemma":0.00003251963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001633237,"about_ca_topic_score_gemma":4.245294e-7,"domain_scores_codex":[0.9990355,0.000002668004,0.000177352,0.0001451898,0.0005311196,0.0001082157],"domain_scores_gemma":[0.9995605,0.00000630966,0.0002061728,0.000006974386,0.0002029919,0.00001707486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002631899,0.00001523783,0.004311567,0.0000405288,0.000004605609,1.264211e-9,0.000008693377,0.00007940104,0.9896581,0.005485086,0.0003288236,0.00004162059],"study_design_scores_gemma":[0.0001106032,0.00008432115,0.02137697,0.000038728,0.000001917022,0.000003854041,0.00004211753,0.0002088131,0.9711504,0.006793865,0.0001507912,0.00003763238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980199,0.0001245129,0.000002997893,0.0003437164,0.000003616078,0.0001315719,0.00002276737,0.000001493783,0.001349446],"genre_scores_gemma":[0.9986694,0.000002797226,0.0007648839,0.00002505096,0.0000613765,0.000002176083,3.224723e-7,0.000002415239,0.0004715682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01850773,"threshold_uncertainty_score":0.1854799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02130525985554914,"score_gpt":0.3041299344258601,"score_spread":0.282824674570311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}