{"id":"W2102019199","doi":"10.4049/jimmunol.1400343","title":"HLA-B27, but Not HLA-B7, Immunodominance to Influenza Is ERAP Dependent","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Toronto Western Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; University Health Network","keywords":"Immunodominance; HLA-B27; Biology; Immunology; CTL*; Major histocompatibility complex; Epitope; Immune system; Human leukocyte antigen; CD8; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007608201,0.0003148591,0.0001479637,0.0001895109,0.0001127497,0.0002139077,0.0001599838,0.0002107152,0.001903192],"category_scores_gemma":[0.00009101991,0.0001709243,0.0001737723,0.00006943114,0.0002079513,0.0001540637,0.0002612586,0.0006192712,0.0007507524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001365743,"about_ca_system_score_gemma":0.0001114875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003147517,"about_ca_topic_score_gemma":0.0004442775,"domain_scores_codex":[0.9998475,0.00001969496,0.000009046863,0.00002747271,0.00003820484,0.0000579735],"domain_scores_gemma":[0.9998524,0.00001704761,0.00004713891,0.00001672438,0.00001961086,0.00004706462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004146132,0.000007288817,0.0001866525,0.00001145832,0.000002443682,0.0000412507,0.000004469379,0.00001192668,0.9992098,0.00002824007,0.00001810673,0.0004368166],"study_design_scores_gemma":[0.0000207715,0.0003183391,0.02181933,0.00001059917,0.00002733598,0.001296854,0.00007147355,0.0008131698,0.9727786,0.00009989956,0.002737449,0.000006182645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960428,0.0008690758,0.001152662,0.00006687343,0.00001257941,0.0000114316,0.0001473752,0.00003745369,0.00165972],"genre_scores_gemma":[0.9950674,0.0008818191,0.0006073203,0.00004938169,0.00001266891,0.0000229401,0.0003618388,0.00002736756,0.002969272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001903192,"threshold_uncertainty_score":0.006366849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01688765952383987,"score_gpt":0.2807127239395362,"score_spread":0.2638250644156964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}