{"id":"W2102075909","doi":"10.1081/ncn-120023043","title":"Branchpoint Sugar Stereochemistry Determines the Hydrolytic Susceptibility of Branched RNA Fragments by the Yeast Debranching Enzyme (YDBR)","year":2003,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Phosphodiester bond; Arabinose; Ribose; Yeast; Chemistry; Stereochemistry; Biochemistry; RNA; RNA splicing; Hydrolysis; Saccharomyces cerevisiae; Enzyme; Xylose; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002811192,0.0003388413,0.0002031759,0.000129605,0.00008816174,0.0004057209,0.0001154938,0.000228002,0.001102946],"category_scores_gemma":[0.0004335711,0.0002018019,0.0002000558,0.0001290038,0.0002604595,0.0002104004,0.0001536793,0.0003978351,0.0003478469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001937626,"about_ca_system_score_gemma":0.0001192397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005246169,"about_ca_topic_score_gemma":0.0006235933,"domain_scores_codex":[0.9998547,0.00003484808,0.0000123615,0.00003910549,0.00002565856,0.00003332255],"domain_scores_gemma":[0.9995546,0.000171095,0.0001348682,0.00003226434,0.00004155294,0.00006554562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001064694,0.000004671195,0.0001752012,0.000009152038,0.000002612266,0.00001947371,0.000009968571,0.00009916001,0.9989649,0.00003100385,0.000002159021,0.0005752432],"study_design_scores_gemma":[0.00000568036,0.0001376505,0.001300708,0.000001694147,0.000007080509,0.00007212098,0.00001251116,0.0002960137,0.9979985,0.00001616338,0.0001483471,0.000003362018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974951,0.0003139944,0.001713846,0.00001118358,0.000002400071,0.000008601957,0.00006470107,0.0000175772,0.0003726341],"genre_scores_gemma":[0.997442,0.000248132,0.001605608,0.00001198686,0.000002141922,0.00000726936,0.0002100105,0.00001953756,0.0004532869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001102946,"threshold_uncertainty_score":0.003689766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009751519323507348,"score_gpt":0.2427876287742098,"score_spread":0.2330361094507025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}