{"id":"W2102083393","doi":"10.1006/abbi.1999.1611","title":"The Enzymatic Formation of Novel Bile Acid Primary Amides","year":2000,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; Comprehensive Cancer Center, University of Alabama at Birmingham; National Cancer Institute; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Natural Sciences and Engineering Research Council of Canada; Duquesne University; National Institute of General Medical Sciences; Human Growth Foundation; Whitehall Foundation; Bayer Corporation; University of Alabama","keywords":"Chemistry; Glyoxylate cycle; Glycine; Bile acid; Stereochemistry; Cholic acid; Conjugate; Carboxylate; Amide; Lithocholic acid; Substrate (aquarium); Enzyme; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000343145,0.00007159394,0.0001392154,0.000009646578,0.00005309414,0.000003652085,0.00005983329,0.00002577539,0.000005467741],"category_scores_gemma":[0.00000365534,0.00004457756,0.00006857918,0.00005596648,0.0002395789,0.00002928273,0.00000854588,0.00005171791,4.5751e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002519413,"about_ca_system_score_gemma":0.00002463485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001852962,"about_ca_topic_score_gemma":2.63861e-7,"domain_scores_codex":[0.9995531,0.000003394544,0.0001795703,0.00007839787,0.0000990259,0.00008645149],"domain_scores_gemma":[0.9996898,0.00004157662,0.0000698434,0.0001520013,0.00001336757,0.00003348128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001708079,0.0001147983,0.00003609821,0.0006977257,0.0000197781,5.69606e-7,0.0002145356,9.534161e-7,0.962247,0.0002232454,0.000007924076,0.03626654],"study_design_scores_gemma":[0.0004646865,0.00006181106,0.00123006,0.0002107775,0.00004180049,0.000006133068,0.0001474829,0.0001992085,0.9964237,0.0009933484,0.0001709134,0.00005012114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926974,0.0004542609,0.0005174872,0.0001293954,0.00001164849,0.00008668163,0.00002670356,0.000008767063,0.006067683],"genre_scores_gemma":[0.9968349,0.000586872,0.001757473,0.00002556454,0.00003303577,0.000003211371,0.00004956975,0.000004514377,0.0007048546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03621642,"threshold_uncertainty_score":0.181782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006269665886033876,"score_gpt":0.2040325996069492,"score_spread":0.1977629337209154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}