{"id":"W2102083393","doi":"10.1006/abbi.1999.1611","title":"The Enzymatic Formation of Novel Bile Acid Primary Amides","year":2000,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; Comprehensive Cancer Center, University of Alabama at Birmingham; National Cancer Institute; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Natural Sciences and Engineering Research Council of Canada; Duquesne University; National Institute of General Medical Sciences; Human Growth Foundation; Whitehall Foundation; Bayer Corporation; University of Alabama","keywords":"Chemistry; Glyoxylate cycle; Glycine; Bile acid; Stereochemistry; Cholic acid; Conjugate; Carboxylate; Amide; Lithocholic acid; Substrate (aquarium); Enzyme; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000508495,0.0006044258,0.0002551129,0.0001793391,0.0002262941,0.0003958326,0.0003008913,0.0004054868,0.001294442],"category_scores_gemma":[0.0004570756,0.0001903983,0.000408198,0.0001132398,0.000306987,0.0006071705,0.000488895,0.0007009592,0.000679487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000410884,"about_ca_system_score_gemma":0.000315273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000185919,"about_ca_topic_score_gemma":0.0002707372,"domain_scores_codex":[0.9998515,0.00003545221,0.00001053105,0.00002924957,0.00002547867,0.00004785317],"domain_scores_gemma":[0.999743,0.00004836958,0.00004570107,0.00003880154,0.00003929031,0.00008486204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005183431,0.00007959442,0.0004628937,0.00009156999,0.00003499616,0.0007422303,0.0001186278,0.0004114181,0.986039,0.002497628,0.0001779023,0.008825605],"study_design_scores_gemma":[0.00002419855,0.000318592,0.0007936442,0.000005478099,0.00001532664,0.0006754817,0.00003338706,0.0004762456,0.9936491,0.0003917459,0.003605979,0.00001103786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706274,0.002782145,0.01882122,0.0003660282,0.0002845667,0.0000608251,0.0002021162,0.00008508585,0.006770699],"genre_scores_gemma":[0.9894107,0.001132944,0.005464828,0.0000619826,0.00003590036,0.00002495003,0.0002974555,0.00001818834,0.003553079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001294442,"threshold_uncertainty_score":0.004330337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006269665886033876,"score_gpt":0.2040325996069492,"score_spread":0.1977629337209154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}