{"id":"W2102141504","doi":"10.1097/00000542-200412000-00021","title":"Chronic Oral Gabapentin Reduces Elements of Central Sensitization in Human Experimental Hyperalgesia","year":2004,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"GlaxoSmithKline","keywords":"Medicine; Gabapentin; Hyperalgesia; Sensitization; Central sensitization; Anesthesia; Pharmacology; Nociception; Immunology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002253381,0.0005078653,0.0006293275,0.0002069814,0.0001599769,0.0002145064,0.0001704806,0.0002434832,0.001915085],"category_scores_gemma":[0.0004027401,0.000164736,0.0001649654,0.0001423892,0.0004922009,0.0002167442,0.0001652198,0.0005527486,0.0002362565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002062726,"about_ca_system_score_gemma":0.0002261849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004111933,"about_ca_topic_score_gemma":0.0008044412,"domain_scores_codex":[0.9998456,0.00005062608,0.00001119677,0.00001882935,0.00002811286,0.00004561606],"domain_scores_gemma":[0.999826,0.00003283382,0.00006679708,0.00001962045,0.0000114755,0.00004332064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03740185,0.007226051,0.003166274,0.0003947587,0.0001102091,0.0002372008,0.000104263,0.000352794,0.900798,0.00005674751,0.0003616172,0.04979026],"study_design_scores_gemma":[0.00619858,0.3102395,0.1634815,0.00008714875,0.0003389187,0.002348031,0.0002647374,0.001791274,0.5118396,0.000120084,0.003248784,0.00004178521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982925,0.0008709315,0.0002300196,0.00003858779,0.00001804855,0.00006500486,0.00004728217,0.00004285113,0.0003947935],"genre_scores_gemma":[0.9984578,0.0005337955,0.0003088357,0.00004061956,0.0000181149,0.00004152976,0.00009706516,0.000006437891,0.0004958984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001915085,"threshold_uncertainty_score":0.006406665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0179571278180901,"score_gpt":0.2965043349573084,"score_spread":0.2785472071392183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}