{"id":"W2102149158","doi":"10.1016/j.ijrobp.2012.11.042","title":"A Phase 3 Trial of Whole Brain Radiation Therapy and Stereotactic Radiosurgery Alone Versus WBRT and SRS With Temozolomide or Erlotinib for Non-Small Cell Lung Cancer and 1 to 3 Brain Metastases: Radiation Therapy Oncology Group 0320","year":2013,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":269,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; McGill University","funders":"National Cancer Institute","keywords":"Medicine; Radiosurgery; Temozolomide; Erlotinib; Lung cancer; Oncology; Clinical endpoint; Internal medicine; Radiation therapy; Cancer; Nuclear medicine; Randomized controlled trial; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003311913,0.00384921,0.005354591,0.0009140797,0.0007511317,0.001771478,0.002381071,0.002598878,0.01016924],"category_scores_gemma":[0.001965987,0.001203924,0.004339826,0.001031098,0.002369845,0.002088209,0.0007926663,0.007289374,0.002829493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001811661,"about_ca_system_score_gemma":0.00301912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002844721,"about_ca_topic_score_gemma":0.007695236,"domain_scores_codex":[0.9989817,0.00047456,0.00004366978,0.0002164438,0.00007218803,0.0002113971],"domain_scores_gemma":[0.9985037,0.0003016687,0.0002478953,0.0001343299,0.0000801631,0.0007323333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9581347,0.01798435,0.0004779253,0.000257005,0.001180987,0.00004237088,0.0001047946,0.001038266,0.004075805,0.0001770841,0.001935776,0.01459096],"study_design_scores_gemma":[0.8582429,0.1374052,0.001656943,0.00001529025,0.0003943717,0.00005061343,0.00003744968,0.0005785671,0.0004668292,0.0003297717,0.0008008892,0.00002127442],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824206,0.002606214,0.00104271,0.001650537,0.0007729332,0.0042905,0.003496558,0.0003231488,0.003396667],"genre_scores_gemma":[0.9658601,0.003210057,0.003866211,0.002963965,0.0007140681,0.009045051,0.006308408,0.0001957181,0.007836338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01016924,"threshold_uncertainty_score":0.03401947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03659139454495125,"score_gpt":0.36074108148651,"score_spread":0.3241496869415587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}