{"id":"W2102269092","doi":"10.1016/j.biomaterials.2010.05.070","title":"The use of immobilized neurotrophins to support neuron survival and guide nerve fiber growth in compartmentalized chambers","year":2010,"lang":"en","type":"article","venue":"Biomaterials","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nerve growth factor; Neurotrophin; Axon; Tropomyosin receptor kinase A; Compartment (ship); Axoplasmic transport; Neuron; Neuroscience; Regeneration (biology); Neurite; Cell biology; Growth cone; Signal transduction; Chemistry; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003567018,0.0001440004,0.0002374718,0.0000576483,0.000151569,0.0002188488,0.0001680021,0.00005416948,0.00008829514],"category_scores_gemma":[0.0003681974,0.00009665299,0.00004138946,0.0001587716,0.0002277867,0.0001843806,0.0001165822,0.00002123459,0.00002238275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008336381,"about_ca_system_score_gemma":0.00002766593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002570737,"about_ca_topic_score_gemma":0.0001000197,"domain_scores_codex":[0.9984376,0.0003700641,0.0004696311,0.0003166046,0.0001804396,0.0002256798],"domain_scores_gemma":[0.9992619,0.0002218006,0.0001388718,0.0002689718,0.00002834199,0.00008012162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002387678,0.00005018972,0.000314446,0.000009758475,0.000001800638,0.00001481721,0.00004832467,0.000004466638,0.997614,0.0009396023,0.0006247234,0.0001390696],"study_design_scores_gemma":[0.0005764564,0.0001809667,0.006654243,0.000004950361,0.000005449831,0.00002096919,0.000003228605,0.00003779157,0.9773538,0.00003613406,0.01502151,0.0001045571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997017,0.000002008829,0.000001578936,0.0005339283,0.001677434,0.0005616194,0.00008123384,0.00003202596,0.00009318001],"genre_scores_gemma":[0.9990811,0.00001199036,0.000246192,0.0001688876,0.00006328007,0.00004016361,0.000008779396,0.00001759351,0.0003619715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02026029,"threshold_uncertainty_score":0.3941395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06945256565375514,"score_gpt":0.3108158625665859,"score_spread":0.2413632969128308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}