{"id":"W2102296035","doi":"10.1186/1471-2164-5-85","title":"Functional characterization in Caenorhabditis elegans of transmembrane worm-human orthologs","year":2004,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Center for Research Resources; Genome British Columbia; Genome Canada; National Institutes of Health; Pfizer","keywords":"Caenorhabditis elegans; Biology; Gene; Genetics; Genome; Caenorhabditis; RNA interference; Human genome; Conserved sequence; Transmembrane protein; Model organism; Gene family; Computational biology; RNA; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001515828,0.0002170352,0.0001580861,0.0003166442,0.0001773064,0.0001484057,0.0001197619,0.0001981729,0.0006868368],"category_scores_gemma":[0.000159854,0.00007701776,0.0002171217,0.0001974273,0.0001335538,0.0001167099,0.0001134932,0.0001574421,0.0002738574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002060325,"about_ca_system_score_gemma":0.0001692506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007773668,"about_ca_topic_score_gemma":0.00107419,"domain_scores_codex":[0.9999409,0.000004096387,0.000006602372,0.00002322112,0.00001560367,0.000009692289],"domain_scores_gemma":[0.9998851,0.00003443614,0.00002478985,0.00001225287,0.00002008332,0.00002341812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001487602,0.00001348892,0.001948358,0.0000954666,0.000006637878,0.0001515863,0.00003046222,0.0001281985,0.9946622,0.0001252427,0.00006597095,0.002623594],"study_design_scores_gemma":[0.00003478353,0.0003665318,0.09304815,0.00002623751,0.00008464098,0.002159357,0.0001140531,0.002265296,0.8924317,0.000190071,0.009262013,0.00001708412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947351,0.001167772,0.001701921,0.00003011361,0.000009468181,0.00002021752,0.00165335,0.00004383991,0.0006382297],"genre_scores_gemma":[0.9846337,0.0008047807,0.009230254,0.00004056538,0.000005953148,0.00004289101,0.004337065,0.00002808765,0.0008765174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007773668,"threshold_uncertainty_score":0.00229764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01342233876462507,"score_gpt":0.2145517917912116,"score_spread":0.2011294530265866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}