{"id":"W2102353725","doi":"10.1165/rcmb.2013-0015oc","title":"NLRP3 and ASC Differentially Affect the Lung Transcriptome during Pneumococcal Pneumonia","year":2013,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Transcriptome; Pneumonia; Pneumococcal pneumonia; Affect (linguistics); Medicine; Lung; Biology; Streptococcus pneumoniae; Microbiology; Bioinformatics; Immunology; Internal medicine; Genetics; Antibiotics; Psychology; Gene; Communication; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001635306,0.0001644241,0.0002339943,0.00006435559,0.0001141989,0.00003888335,0.0001924399,0.00007539838,0.00001277717],"category_scores_gemma":[0.00001641126,0.0001095743,0.0001090677,0.00007591824,0.0004614111,0.000007235953,0.00005846715,0.000169586,0.00000128487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008831117,"about_ca_system_score_gemma":0.00005647332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001876863,"about_ca_topic_score_gemma":0.000002701872,"domain_scores_codex":[0.9989643,0.0002354816,0.0002697405,0.0002300521,0.00007484493,0.0002255731],"domain_scores_gemma":[0.9993011,0.00001680848,0.0002356182,0.0002132654,0.00009775288,0.0001354141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000449682,0.0000239638,0.005031368,0.00001155932,0.00006569893,0.000005221305,0.00004542864,0.000004571953,0.9877287,0.00003720937,0.00005364051,0.006947651],"study_design_scores_gemma":[0.001993609,0.003906029,0.2363108,0.00003264089,0.0001840325,0.0003445598,0.0005694849,0.00003037722,0.7292728,0.0001767272,0.02659083,0.0005881323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904258,0.006887089,0.002004737,0.0003412171,0.00008281946,0.0001461935,0.000003950213,0.000003345384,0.0001048312],"genre_scores_gemma":[0.9983869,0.000771006,0.0001279366,0.0005152044,0.0001175762,0.00001771559,0.000002534343,0.00001786095,0.0000433338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2584559,"threshold_uncertainty_score":0.4468311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004307669374768393,"score_gpt":0.2370142681402937,"score_spread":0.2327065987655253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}