{"id":"W2102375182","doi":"10.1111/j.1742-4658.2008.06377.x","title":"Structure–activity relationships of wheat flavone <i>O</i>‐methyltransferase – a homodimer of convenience","year":2008,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Monomer; Isothermal titration calorimetry; Dimer; Methyltransferase; Stereochemistry; O-methyltransferase; Pterin; Biochemistry; Methylation; Enzyme; Cofactor; Organic chemistry; DNA; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001741696,0.0001536539,0.0001875346,0.0002378098,0.00007616942,0.0003135014,0.0001667504,0.0002671986,0.0008066303],"category_scores_gemma":[0.0003257739,0.0001433412,0.000148345,0.0001823981,0.00009917581,0.0001578027,0.00008234335,0.0001976841,0.0003835268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004069502,"about_ca_system_score_gemma":0.00007691252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008677688,"about_ca_topic_score_gemma":0.0005835946,"domain_scores_codex":[0.9998773,0.00002140824,0.00001439825,0.00003509999,0.0000320634,0.00001961141],"domain_scores_gemma":[0.9998344,0.0000342152,0.0000430664,0.0000245439,0.00002639824,0.00003737198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001572706,0.00005311671,0.001283991,0.00001318156,0.000007850835,0.00002938269,0.00002355995,0.0001626435,0.9966893,0.00007280059,0.00005866524,0.001448067],"study_design_scores_gemma":[0.0000362851,0.0004325932,0.02635329,0.00000472989,0.00002761428,0.0005032098,0.00004950961,0.00698299,0.9628962,0.00009302956,0.002610157,0.00001037964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982353,0.0005680078,0.0005233019,0.00003091144,0.000004193699,0.000003781774,0.0001679146,0.00001977466,0.0004467659],"genre_scores_gemma":[0.9972376,0.0002033639,0.0008436758,0.00001544545,0.000002037282,0.000004090646,0.0007668503,0.000005691331,0.0009213048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008677688,"threshold_uncertainty_score":0.002952635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03122422444629089,"score_gpt":0.2341410347749732,"score_spread":0.2029168103286823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}