{"id":"W2102408597","doi":"10.1128/mcb.20.5.1497-1506.2000","title":"Distinct Roles for Gα <sub>i</sub> 2 and Gβγ in Signaling to DNA Synthesis and Gα <sub>i</sub> 3 in Cellular Transformation by Dopamine D2S Receptor Activation in BALB/c 3T3 Cells","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; McGill University","funders":"","keywords":"Biology; Pertussis toxin; Signal transduction; G protein; Receptor; Molecular biology; MAPK/ERK pathway; Transfection; Cell biology; 5-HT5A receptor; Cell culture; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005040877,0.0003291827,0.0003790213,0.0002251747,0.00008706214,0.0000481312,0.0001002862,0.0003953234,0.000009019731],"category_scores_gemma":[0.00007045823,0.0003485401,0.0000705883,0.0002214097,0.0001047742,0.00002598785,0.00003873428,0.0001453296,0.000002469264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003745581,"about_ca_system_score_gemma":0.00003243264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004617817,"about_ca_topic_score_gemma":0.000111918,"domain_scores_codex":[0.9980261,0.0002536598,0.0005130608,0.000669292,0.00009973499,0.0004381378],"domain_scores_gemma":[0.9994799,0.00005914857,0.00009432533,0.00018925,0.00003887821,0.0001384382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000300976,0.00007833424,0.0002826971,0.00009145062,0.00001847762,0.000005112855,0.0001333418,0.0001569403,0.9597901,0.00005162483,0.00001272923,0.03907822],"study_design_scores_gemma":[0.001293076,0.0002448202,0.0002721475,0.0001020978,0.00002052608,0.000002942307,0.00009510013,0.0006959983,0.9952865,0.0001814882,0.001404156,0.0004011099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800675,0.001817758,0.01690106,0.0002378878,0.0000285863,0.0008322492,0.00007147967,0.00001278346,0.00003068891],"genre_scores_gemma":[0.9981865,0.0003901778,0.0002942721,0.0001759268,0.0000474751,0.0001873964,0.0006748488,0.00003734165,0.000006104917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03867711,"threshold_uncertainty_score":0.9998966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004507370177900485,"score_gpt":0.1984231418672735,"score_spread":0.193915771689373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}