{"id":"W2102421724","doi":"10.1093/nar/gkm117","title":"Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells","year":2007,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Donald E. and Delia B. Baxter Foundation","keywords":"Biology; Ku80; Molecular biology; Ku70; Jurkat cells; Chromatin immunoprecipitation; Chromatin; Promoter; Chromatin remodeling; Response element; Transcription factor; Cell biology; T cell; Gene expression; DNA; DNA-binding protein; Gene; DNA repair; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001468077,0.0003960331,0.0001589904,0.0002449871,0.0001609767,0.0003562857,0.0002025206,0.000219708,0.002444469],"category_scores_gemma":[0.0001448911,0.0002229814,0.0001776182,0.000127363,0.0001654556,0.0001780418,0.0002501741,0.00055107,0.0009789594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003516377,"about_ca_system_score_gemma":0.0001578279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003627225,"about_ca_topic_score_gemma":0.0005081841,"domain_scores_codex":[0.9997167,0.00004423288,0.0000151034,0.00007797749,0.00007858098,0.00006738549],"domain_scores_gemma":[0.9998441,0.00002206447,0.00003455826,0.00002160706,0.00001602578,0.00006171914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004967352,0.00001066576,0.00008314758,0.00001062045,0.000002371995,0.00001188597,0.000006578096,0.00001528781,0.9994712,0.00003809254,0.00001297523,0.0002874297],"study_design_scores_gemma":[0.00003568902,0.000230738,0.009004991,0.00001281908,0.00001463675,0.000358646,0.00003100846,0.0006260378,0.986662,0.0001297019,0.002889233,0.000004729261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877445,0.003146718,0.005505031,0.00009577565,0.00004325428,0.00002272091,0.000351312,0.0001387475,0.002951987],"genre_scores_gemma":[0.9923459,0.0007930673,0.001719451,0.00007579674,0.00002314931,0.00004509129,0.001123952,0.00003878167,0.003834745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002444469,"threshold_uncertainty_score":0.008177578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02424132173525797,"score_gpt":0.3069783263930115,"score_spread":0.2827370046577535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}