{"id":"W2102421724","doi":"10.1093/nar/gkm117","title":"Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells","year":2007,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Donald E. and Delia B. Baxter Foundation","keywords":"Biology; Ku80; Molecular biology; Ku70; Jurkat cells; Chromatin immunoprecipitation; Chromatin; Promoter; Chromatin remodeling; Response element; Transcription factor; Cell biology; T cell; Gene expression; DNA; DNA-binding protein; Gene; DNA repair; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002619799,0.0001690795,0.0003202193,0.0008466406,0.0001624152,0.00001754622,0.000522744,0.0003995329,0.0004406619],"category_scores_gemma":[0.0001579867,0.0001243691,0.00004168049,0.0010227,0.0005757323,0.00008082685,0.0004398483,0.001163545,0.0003826481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001411756,"about_ca_system_score_gemma":0.00007234838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005623952,"about_ca_topic_score_gemma":0.001036142,"domain_scores_codex":[0.9975979,0.0005134137,0.0004234888,0.0004155035,0.0001105861,0.0009390811],"domain_scores_gemma":[0.9989018,0.0004881818,0.0000580608,0.0004191402,0.000096296,0.00003646395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004640296,0.0002250745,0.003834975,0.00002676009,0.00003485081,0.00002622555,0.002036181,0.000002265326,0.9834901,0.0001097303,0.0005734877,0.009176306],"study_design_scores_gemma":[0.001398511,0.0004390639,0.007752052,0.00008646321,0.000003816071,0.00002742036,0.001994968,0.00001385676,0.9642646,0.0001026379,0.02376788,0.0001487525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959887,0.0004204839,0.00001884502,0.0008299174,0.0002036447,0.0006134281,0.00002003211,0.00002244173,0.001882497],"genre_scores_gemma":[0.9952826,0.0001398326,0.00009659647,0.00004906219,0.00001017723,0.00002131424,0.000007884687,0.00002572462,0.004366839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0231944,"threshold_uncertainty_score":0.5071626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02424132173525797,"score_gpt":0.3069783263930115,"score_spread":0.2827370046577535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}