{"id":"W2102423247","doi":"10.18433/j3pw2w","title":"Investigation of Nanosized Crystalline Form to Improve the Oral Bioavailability of Poorly Water Soluble Cilostazol","year":2011,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China","keywords":"Bioavailability; Dissolution; Differential scanning calorimetry; Materials science; Scanning electron microscope; Powder diffraction; Nuclear chemistry; Particle size; Spray drying; Chromatography; Solubility; Adsorption; Solvent; Chemical engineering; Chemistry; Organic chemistry; Crystallography; Composite material","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107542,0.0001379532,0.0001443969,0.0001382089,0.00008121199,0.0001912963,0.0001485399,0.0001961619,0.000535466],"category_scores_gemma":[0.0001672395,0.00008195784,0.0002162175,0.00007937559,0.0001261899,0.0001698049,0.00009648919,0.0001819937,0.0001082048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000255964,"about_ca_system_score_gemma":0.0001770908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005588045,"about_ca_topic_score_gemma":0.001015345,"domain_scores_codex":[0.9999157,0.000008731517,0.000007008,0.00001992009,0.00003926911,0.000009341179],"domain_scores_gemma":[0.99993,0.00001290662,0.00002483611,0.000004639078,0.00002117258,0.00000639832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005922539,0.00002970444,0.0002745782,0.0001017536,0.000007166918,0.00005311087,0.000009173107,0.000269021,0.9950145,0.0001302757,0.00008658266,0.003965019],"study_design_scores_gemma":[0.00002225436,0.0005306612,0.00148274,0.000007029652,0.00002273005,0.0001756232,0.00001749803,0.003942464,0.9907168,0.00003154873,0.003044636,0.000006181547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987371,0.002816211,0.007334418,0.0001436759,0.00004533542,0.00007514781,0.0001874862,0.00006168488,0.001965132],"genre_scores_gemma":[0.9884862,0.001154284,0.008555029,0.00005619508,0.00001443096,0.00004221926,0.0001912141,0.00002221682,0.001478349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005588045,"threshold_uncertainty_score":0.001857102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.279877224346336,"score_gpt":0.4410618144129158,"score_spread":0.1611845900665798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}