{"id":"W2102449842","doi":"10.1517/13543776.10.5.675","title":"Tyrosine phosphatases: cellular functions and therapeutic potential","year":2000,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Patents","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Smiths Detection (Canada)","funders":"","keywords":"Protein tyrosine phosphatase; Tyrosine; Tyrosine phosphorylation; Receptor tyrosine kinase; Phosphorylation; Protein phosphorylation; Biochemistry; Tyrosine kinase; SH2 domain; Platelet-derived growth factor receptor; Cell biology; Proto-oncogene tyrosine-protein kinase Src; Phosphatase; Chemistry; Biology; Signal transduction; Protein kinase A; Receptor; Growth factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007566581,0.0006418714,0.000787914,0.0006519501,0.0003173154,0.001395997,0.0004543558,0.001143383,0.003713944],"category_scores_gemma":[0.0005526967,0.0001541313,0.0003367478,0.0007160751,0.0007193273,0.001153459,0.0005999937,0.001821751,0.001646564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007590146,"about_ca_system_score_gemma":0.0006226004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003204064,"about_ca_topic_score_gemma":0.0004447297,"domain_scores_codex":[0.9997819,0.00004398798,0.00001493778,0.0000339468,0.00008618319,0.00003912413],"domain_scores_gemma":[0.9998544,0.00004227073,0.00002838074,0.0000102666,0.00003433242,0.00003028646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006111116,0.0001626523,0.0005974208,0.003747205,0.00008493247,0.001311482,0.000135018,0.0008967809,0.0752115,0.03801025,0.02511998,0.8541116],"study_design_scores_gemma":[0.0001762178,0.000683601,0.00167345,0.0006602794,0.0001601651,0.006677677,0.0001295575,0.0005870847,0.02673659,0.0215282,0.9409521,0.0000350109],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004202279,0.9836357,0.001395783,0.00390366,0.0004657827,0.00001222854,0.00006665253,0.00003666663,0.006281339],"genre_scores_gemma":[0.05379323,0.9367281,0.001832495,0.001195965,0.0009920808,0.0000391228,0.0001378729,0.000009585883,0.005271646],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003713944,"threshold_uncertainty_score":0.01242435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0197475529811363,"score_gpt":0.2656236591770438,"score_spread":0.2458761061959075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}