{"id":"W2102498292","doi":"10.1038/embor.2009.87","title":"The SecY complex forms a channel capable of ionic discrimination","year":2009,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biophysics; Chemistry; Ionic bonding; Channel (broadcasting); Cell biology; Computational biology; Biology; Computer science; Telecommunications; Ion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001994252,0.00006647935,0.00006773377,0.00002081104,0.0001217679,0.00001346622,0.00004126267,0.0000589037,0.00001286153],"category_scores_gemma":[0.00005464611,0.00004532411,0.00006089282,0.00005962399,0.00003096725,0.000004459438,0.00001564514,0.00002916324,0.000001517576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001006975,"about_ca_system_score_gemma":0.00002782082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000749104,"about_ca_topic_score_gemma":0.00001336159,"domain_scores_codex":[0.9993903,0.00001482248,0.0002186575,0.0001425805,0.0001199018,0.0001137141],"domain_scores_gemma":[0.9994757,0.00000378089,0.0001621791,0.0002289862,0.0001007272,0.00002867967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003076275,0.0004127939,0.001085279,0.00005985399,0.0001164473,0.00003195392,0.0007664358,0.00471618,0.8650049,0.0123462,0.06846292,0.04668939],"study_design_scores_gemma":[0.001124509,0.001433355,0.1183395,0.00005398027,0.00006160601,0.0007424068,0.001068905,0.009324864,0.5161502,0.02983446,0.3212158,0.000650373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733554,0.0003475192,0.00722341,0.001427325,0.0007508154,0.0002964364,0.000002888523,0.00002236128,0.01657381],"genre_scores_gemma":[0.9968197,0.00004318735,0.00003200016,0.0001179983,0.0001740135,0.00000687986,0.0001494082,0.000005366672,0.002651418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3488547,"threshold_uncertainty_score":0.1848264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685221416603533,"score_gpt":0.2570666582684389,"score_spread":0.2402144441024036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}