{"id":"W2102548388","doi":"10.1128/jvi.75.22.10892-10905.2001","title":"Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":782,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Deutsches Krebsforschungszentrum; National Institutes of Health; Hearst Foundations","keywords":"Epitope; Gp41; Monoclonal antibody; Biology; Virology; Glycoprotein; Linear epitope; Antibody; Epitope mapping; Molecular biology; Conformational epitope; Neutralizing antibody; Virus; Recombinant DNA; Biochemistry; Immunology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115293,0.0007074553,0.0003695156,0.0002734035,0.0001411028,0.0003178971,0.0003544304,0.0006342608,0.0009069606],"category_scores_gemma":[0.0002047004,0.000188164,0.0003167529,0.0001428408,0.0001883154,0.0001936569,0.0003215313,0.0006729834,0.0003085766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003235466,"about_ca_system_score_gemma":0.0001385386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00037144,"about_ca_topic_score_gemma":0.0004160165,"domain_scores_codex":[0.9997328,0.00004481018,0.00002103906,0.00005936204,0.0000465504,0.00009530649],"domain_scores_gemma":[0.9998897,0.00003169735,0.00002172152,0.0000150522,0.0000211465,0.00002069014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003508366,0.00003928764,0.0003139351,0.00002265767,0.000006121642,0.0000376662,0.000007462308,0.0000704909,0.9972526,0.00004487388,0.00002433857,0.002145499],"study_design_scores_gemma":[0.000085364,0.001317779,0.01236322,0.00002061525,0.00006152838,0.001218393,0.00003059827,0.001876947,0.9799913,0.0001317674,0.002891888,0.00001047339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987988,0.001303704,0.008751259,0.00005481791,0.00002708892,0.00007803092,0.0001172075,0.0001107279,0.001569091],"genre_scores_gemma":[0.9902835,0.001095098,0.006495831,0.000185433,0.00002690102,0.00007471822,0.0004306114,0.00001250857,0.001395396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009069606,"threshold_uncertainty_score":0.003034115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02710039626513931,"score_gpt":0.2972148738846824,"score_spread":0.2701144776195431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}