{"id":"W2102615381","doi":"10.1093/toxsci/kfg050","title":"From Anticholinesterase Toxicity to Alzheimer's Disease: Important Interactions of Cholinergic and NMDA Receptor Systems","year":2003,"lang":"en","type":"review","venue":"Toxicological Sciences","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"NMDA receptor; Cholinergic; Dizocilpine; Neuroscience; Disease; Alzheimer's disease; Pharmacology; Receptor; Toxicity; Cholinergic system; Medicine; Psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003405849,0.0005006305,0.001849554,0.0002426554,0.0001796498,0.0001142934,0.0002810499,0.000166243,0.0003489683],"category_scores_gemma":[0.000531698,0.0003028579,0.0003766225,0.0008188437,0.0004254012,0.0001429084,0.0001466673,0.000296082,0.0000329645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004761682,"about_ca_system_score_gemma":0.0003913399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003533998,"about_ca_topic_score_gemma":0.000005935477,"domain_scores_codex":[0.996689,0.0003574569,0.001094049,0.0009999602,0.0004750279,0.0003845066],"domain_scores_gemma":[0.997609,0.0005322222,0.0004593773,0.0003870108,0.0001254482,0.0008869871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001898313,0.01875287,0.03536113,0.02715058,0.003450623,0.001727204,0.0007883496,0.0003100675,0.007784104,0.002897468,0.03179212,0.8680872],"study_design_scores_gemma":[0.0006296751,0.0009992366,0.001963722,0.009555372,0.002750427,0.00007775577,0.00009097495,0.000100044,0.0003197016,0.00003265016,0.982585,0.0008954506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1928973,0.8043151,0.000007343118,0.0001514157,0.0005873174,0.001240273,0.0006290788,0.00004367642,0.0001284914],"genre_scores_gemma":[0.01640151,0.9814166,0.0003220543,0.0006447153,0.0006306008,0.000204748,0.0001631884,0.00002558932,0.0001910087],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9507928,"threshold_uncertainty_score":0.9999424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1720163347056337,"score_gpt":0.4293689494215862,"score_spread":0.2573526147159526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}