{"id":"W2102679105","doi":"10.1128/jvi.79.22.14446-14450.2005","title":"Retroviral Restriction Factor TRIM5α Is a Trimer","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Center for AIDS Research, University of Washington; Bristol-Myers Squibb; Bristol-Myers Squibb Foundation; National Institutes of Health; International AIDS Vaccine Initiative","keywords":"Capsid; Retrovirus; Trimer; Biology; Mutant; Murine leukemia virus; Coiled coil; Protein stability; Cell biology; Wild type; Virology; Virus; Genetics; Gene; Physics; Dimer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001857585,0.0004369113,0.0003360036,0.0003260218,0.0004219766,0.0005605176,0.000245761,0.0004016081,0.002966839],"category_scores_gemma":[0.0001954979,0.0002051592,0.0003868625,0.0002480221,0.0002217024,0.0002429239,0.0002677298,0.0005026653,0.003206411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005213378,"about_ca_system_score_gemma":0.0002488619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008336739,"about_ca_topic_score_gemma":0.000483009,"domain_scores_codex":[0.9998066,0.00002057005,0.00001562353,0.00005650091,0.00006576222,0.00003496031],"domain_scores_gemma":[0.999877,0.000007560602,0.00003769149,0.00001994702,0.00002166889,0.00003614861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001810192,0.00001776952,0.001194471,0.000113039,0.00002254117,0.0002571409,0.00003105045,0.00008960135,0.9859141,0.0005796644,0.0008815121,0.01071796],"study_design_scores_gemma":[0.00003831461,0.0003909018,0.02218685,0.00005303657,0.00006982218,0.005221424,0.0000962422,0.001625445,0.8996798,0.0004414257,0.07016838,0.00002834425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93445,0.02235284,0.02378113,0.0008383743,0.0003812373,0.0001438783,0.002627371,0.001450942,0.01397414],"genre_scores_gemma":[0.9591726,0.004904151,0.01037666,0.000446144,0.00009037562,0.0000430681,0.005491768,0.00007906523,0.01939624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002966839,"threshold_uncertainty_score":0.009925127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01999804927093493,"score_gpt":0.2896095904137997,"score_spread":0.2696115411428648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}