{"id":"W2102742135","doi":"10.1152/ajpcell.00083.2014","title":"Role of anion exchangers in Cl<sup>−</sup> and HCO<sub>3</sub><sup>−</sup> secretion by the human airway epithelial cell line Calu-3","year":2014,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Royal Society; University of Manchester; McGill University","keywords":"DIDS; Chemistry; Epithelial polarity; Apical membrane; Ion transporter; Intracellular pH; Secretion; Biophysics; Intracellular; Forskolin; Efflux; Respiratory epithelium; Niflumic acid; Sodium–hydrogen antiporter; Biochemistry; Epithelium; Membrane; Biology; Sodium; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003176417,0.0002414069,0.000384756,0.000193385,0.0002680128,0.0008650845,0.0002305153,0.0004773358,0.0007261435],"category_scores_gemma":[0.0001865046,0.0002006394,0.0003747247,0.0001675835,0.0002922286,0.0004980794,0.0003017957,0.000467484,0.0003062959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002806543,"about_ca_system_score_gemma":0.0003151895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001129139,"about_ca_topic_score_gemma":0.001113192,"domain_scores_codex":[0.9998211,0.00002892684,0.00002429521,0.0000304377,0.00006709005,0.00002809103],"domain_scores_gemma":[0.9998888,0.00002750808,0.00002292461,0.0000141076,0.00002499209,0.00002168515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005492471,0.00001351675,0.001731472,0.00005853581,0.000007241748,0.0001919647,0.00005524719,0.00004756101,0.9955864,0.0001450911,0.00003169422,0.001581986],"study_design_scores_gemma":[0.0001453873,0.0005392191,0.09830383,0.00002885368,0.00007416245,0.001449114,0.0003534867,0.003925791,0.8878406,0.0005838923,0.006729371,0.00002623503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855818,0.009463168,0.002709963,0.0005344069,0.00003221242,0.00002823162,0.0005192694,0.00006017987,0.001070828],"genre_scores_gemma":[0.9939551,0.002153995,0.001831336,0.0002106327,0.00002517449,0.00002390235,0.0006616057,0.00001358725,0.001124788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001129139,"threshold_uncertainty_score":0.002429187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003745493067593261,"score_gpt":0.201186926707205,"score_spread":0.1974414336396118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}