{"id":"W2102746809","doi":"10.1074/jbc.m404963200","title":"Lipid Trafficking Controls Endotoxin Acylation in Outer Membranes of Escherichia coli","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Escherichia coli; Acylation; Chemistry; Bacterial outer membrane; Lipid A; Membrane; Microbiology; Biochemistry; Bacteria; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230961,0.0002844076,0.000225313,0.0001557345,0.0001338524,0.0005041737,0.0001294338,0.00028855,0.0003272709],"category_scores_gemma":[0.0003166355,0.0001559434,0.0001595634,0.0001655936,0.0001999879,0.0002710613,0.0003239194,0.0003321619,0.0005075422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004464947,"about_ca_system_score_gemma":0.0001779559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007213967,"about_ca_topic_score_gemma":0.0006271235,"domain_scores_codex":[0.9998304,0.00004375861,0.00001883041,0.00002906602,0.00003833989,0.00003953649],"domain_scores_gemma":[0.9998066,0.00003617821,0.00007023476,0.00002161025,0.0000366419,0.00002886167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007718776,0.000006307363,0.0001931197,0.000009431557,7.447856e-7,0.00002469908,0.00001578849,0.00002963632,0.9992031,0.00003630409,0.000005891108,0.0003977972],"study_design_scores_gemma":[0.000009107292,0.0001084867,0.01108849,0.000007909217,0.000007000679,0.0001814425,0.00008870783,0.0008896903,0.9864331,0.00008975742,0.001089793,0.00000662976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974173,0.000511096,0.001276367,0.00009395064,0.000008328357,0.00001003456,0.0001311773,0.00003635124,0.0005153187],"genre_scores_gemma":[0.9968266,0.0003922468,0.001297772,0.00005857414,0.000005401424,0.00001370096,0.0003491684,0.00002709426,0.001029461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007213967,"threshold_uncertainty_score":0.003239572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01477365434995947,"score_gpt":0.2531009865373774,"score_spread":0.238327332187418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}