{"id":"W2102773481","doi":"10.1093/cid/civ534","title":"Telavancin: Mechanisms of Action, In Vitro Activity, and Mechanisms of Resistance","year":2015,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Diagnostic Services Manitoba","funders":"","keywords":"Microbiology; Vancomycin; Staphylococcus aureus; Enterococcus faecalis; Medicine; Minimum inhibitory concentration; Methicillin-resistant Staphylococcus aureus; Antimicrobial; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004982249,0.0001840883,0.0008193696,0.0001605196,0.00003017011,0.000008612133,0.00008720338,0.0001852936,0.00002083524],"category_scores_gemma":[0.002432193,0.0001717702,0.0001934371,0.0003481884,0.0003673822,0.0001230838,0.00008803363,0.0002497283,0.000005311678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009111148,"about_ca_system_score_gemma":0.0003409479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006446858,"about_ca_topic_score_gemma":0.0002377919,"domain_scores_codex":[0.9981829,0.0001705386,0.0007267238,0.0003792387,0.0003076884,0.0002329464],"domain_scores_gemma":[0.9980212,0.0005378082,0.0003976086,0.0003912622,0.0003168453,0.0003352898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01450262,0.009374531,0.2308932,0.002403379,0.0005161528,0.0002289109,0.0001769979,0.00003562156,0.6928081,0.02039211,0.005098997,0.02356934],"study_design_scores_gemma":[0.01027829,0.002630864,0.3816988,0.0008290179,0.0006057551,0.00001656666,0.0004383777,0.0000990438,0.431431,0.1709135,0.0005182631,0.0005404698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800417,0.0003912247,0.01730593,0.0002269201,0.0003671919,0.0005018309,0.00007674555,0.00006979524,0.001018595],"genre_scores_gemma":[0.9987809,0.0001799979,0.0005581525,0.0001762345,0.00006704632,0.00001852661,0.000007054935,0.0000272283,0.0001848693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2613771,"threshold_uncertainty_score":0.7004584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05487205987964483,"score_gpt":0.3702009779023212,"score_spread":0.3153289180226764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}