{"id":"W2102800404","doi":"10.1371/journal.ppat.1003684","title":"Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-Reactive Neutralizing Human Monoclonal Antibody","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Virology and Viral Diseases","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Argonne National Laboratory; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; U.S. Navy; Henry M. Jackson Foundation; Uniformed Services University of the Health Sciences; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services; U.S. Department of Defense","keywords":"Hendra Virus; Virology; Monoclonal antibody; Glycoprotein; Neutralizing antibody; Antibody; Viral entry; Ebolavirus; Biology; Avidity; Outbreak; Ebola virus; Virus; Immunology; Viral replication; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000162219,0.0004405416,0.0005947534,0.0002037916,0.000505141,0.0006212471,0.0009780113,0.0006222003,0.003509962],"category_scores_gemma":[0.0003612528,0.0002685451,0.0002453658,0.0003410971,0.0002649045,0.0003145405,0.0002703523,0.001485271,0.0005764266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001171142,"about_ca_system_score_gemma":0.0009035548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01623324,"about_ca_topic_score_gemma":0.0129725,"domain_scores_codex":[0.9998376,0.00001717788,0.00000421199,0.0000268031,0.00007351087,0.00004067472],"domain_scores_gemma":[0.9998748,0.00003215804,0.00001751314,0.000003901116,0.00003847294,0.00003310625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003790788,0.00136382,0.01452367,0.001044709,0.0007052209,0.005750549,0.000908469,0.0154385,0.8322347,0.009277194,0.06988736,0.04507497],"study_design_scores_gemma":[0.002552534,0.003001608,0.1378331,0.0003115889,0.0007820297,0.007052667,0.00215511,0.2042165,0.3644263,0.004700684,0.2726637,0.0003041911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9478723,0.01132286,0.006054088,0.002740332,0.0006165954,0.0001710159,0.005414198,0.0006691354,0.02513938],"genre_scores_gemma":[0.9540914,0.005064942,0.006794351,0.001120776,0.0000913817,0.00008116625,0.015826,0.0001359371,0.01679409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01623324,"threshold_uncertainty_score":0.03227752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02213711111569035,"score_gpt":0.3190785699598078,"score_spread":0.2969414588441175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}