{"id":"W2102818185","doi":"10.1016/s0304-4165(02)00397-5","title":"Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:α-6-d-mannoside β1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa","year":2002,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Mutant; Glycosylation; Glycan; Gene; Biology; Mutation; Phenotype; Wild type; Molecular biology; Genetics; Glycoprotein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002763423,0.001382847,0.0009510652,0.0008287122,0.0001452379,0.0004194397,0.0006914107,0.0006776187,0.0010061],"category_scores_gemma":[0.0001221371,0.0002061233,0.0001676436,0.000707843,0.0004324317,0.0005835148,0.0002686626,0.0009247881,0.001331407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003107183,"about_ca_system_score_gemma":0.000322897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003692647,"about_ca_topic_score_gemma":0.0008317996,"domain_scores_codex":[0.9999428,0.000005603927,0.000007849593,0.00001565906,0.00002155095,0.000006504228],"domain_scores_gemma":[0.9999287,0.0000174689,0.00002167715,0.00000411828,0.00001408071,0.00001393531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000347935,0.0001420359,0.0005815694,0.005593474,0.00009372529,0.002016687,0.00006694216,0.000467397,0.1161733,0.006677854,0.02593585,0.8419032],"study_design_scores_gemma":[0.00007530807,0.0001916713,0.002085469,0.0006524018,0.0001609747,0.007494855,0.00004566267,0.0001338906,0.02989347,0.001839701,0.9573925,0.00003406202],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006100718,0.9797032,0.005130103,0.0008995304,0.0007331631,0.000038742,0.0002557097,0.0001924858,0.006946337],"genre_scores_gemma":[0.0106511,0.9757612,0.003881717,0.0005795545,0.0001740171,0.00004438732,0.0003484627,0.00001383107,0.008545784],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001382847,"threshold_uncertainty_score":0.003365755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0311767622427233,"score_gpt":0.2925176255838757,"score_spread":0.2613408633411524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}