{"id":"W2102819165","doi":"10.1158/1078-0432.58.11.1","title":"Vaccination of Dendritic Cells Loaded with Interleukin-12-Secreting Cancer Cells Augments <i>In vivo</i> Antitumor Immunity: Characteristics of Syngeneic and Allogeneic Antigen-Presenting Cell Cancer Hybrid Cells","year":2005,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Japan Society for the Promotion of Science","keywords":"Cancer immunotherapy; Immunotherapy; Cancer; Cancer cell; Immunology; Immune system; Dendritic cell; Cancer research; Cancer vaccine; Interleukin 12; Medicine; Antigen; Antigen-presenting cell; T cell; Cytotoxic T cell; Biology; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002557384,0.0003448625,0.001023513,0.0004361741,0.000253121,0.00004190398,0.0006783723,0.0003005583,0.001400099],"category_scores_gemma":[0.0001113923,0.0003092023,0.0001668747,0.0004246421,0.0007758405,0.0002045995,0.0003722134,0.00124482,0.00002179034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002037535,"about_ca_system_score_gemma":0.0006694953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003419854,"about_ca_topic_score_gemma":0.0006801952,"domain_scores_codex":[0.9950494,0.001531688,0.001547496,0.0006538564,0.0002666737,0.0009508881],"domain_scores_gemma":[0.9967243,0.001438921,0.0006607744,0.0005739865,0.0005301331,0.00007185958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002357449,0.0005546446,0.04582499,0.0004046629,0.0002621649,0.00001525961,0.0005043355,0.00005243717,0.9325031,0.00000385039,0.0003329149,0.01718421],"study_design_scores_gemma":[0.003277857,0.0004713884,0.0320359,0.0007132917,0.00006365628,0.000006138835,0.0002839753,0.00004801983,0.9577655,0.000005189968,0.005026232,0.0003029013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754497,0.02243296,0.0000291041,0.0001373382,0.0007692037,0.000750327,0.0002824462,0.00001953779,0.0001293351],"genre_scores_gemma":[0.9575232,0.04026191,0.000092467,0.0001003438,0.0001098881,0.0001253915,0.00002083589,0.00006152586,0.00170446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02526236,"threshold_uncertainty_score":0.999936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05609681653142137,"score_gpt":0.3836351251316134,"score_spread":0.3275383086001921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}