{"id":"W2102825248","doi":"10.1095/biolreprod.109.076216","title":"Rapid Effect of GNRH1 on Follicle-Stimulating Hormone Beta Gene Expression in LbetaT2 Mouse Pituitary Cells Requires the Progesterone Receptor1","year":2009,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Gene knockdown; Biology; Chromatin immunoprecipitation; Gene expression; Internal medicine; Endocrinology; Small interfering RNA; Reporter gene; Regulation of gene expression; Molecular biology; Gene; Promoter; Transfection; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007812312,0.0001888425,0.0002896198,0.00007920104,0.00006339301,0.000003257121,0.0001637063,0.0003008834,0.000001623191],"category_scores_gemma":[0.0001365566,0.0001247472,0.0001096471,0.0001057218,0.0001611642,0.000007605422,0.0000507126,0.0001753376,0.000002604628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001430446,"about_ca_system_score_gemma":0.00001787791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001329189,"about_ca_topic_score_gemma":5.86848e-7,"domain_scores_codex":[0.998358,0.0004143273,0.0003734966,0.0005417108,0.00009361745,0.0002188875],"domain_scores_gemma":[0.998995,0.00004727612,0.0002555726,0.0006217787,0.00004705674,0.00003332627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009478138,0.0001205634,0.001199499,0.00001905258,0.00003824909,9.225623e-7,0.00005212145,0.0004070267,0.9622341,0.00001064459,0.000241876,0.03472807],"study_design_scores_gemma":[0.000854241,0.007373185,0.002003255,0.00003460577,0.00002259213,0.000009195664,0.00001290391,0.00001901112,0.9890549,0.00003332936,0.000463827,0.0001190108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867069,0.0120727,0.00006126247,0.0002914733,0.0002158627,0.0005473385,0.000006038893,0.00001597131,0.00008244471],"genre_scores_gemma":[0.9976934,0.001284567,0.0005874222,0.00001847786,0.0002139416,0.00001791076,0.00009700309,0.00001479127,0.00007245137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03460906,"threshold_uncertainty_score":0.5087044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008571026182428693,"score_gpt":0.2491827265960167,"score_spread":0.240611700413588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}