{"id":"W2102836598","doi":"10.1016/j.ejphar.2004.11.057","title":"A novel plasma membrane Ca2+-pump inhibitor: caloxin 1A1","year":2005,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Heart and Stroke Foundation of Canada","keywords":"Endoplasmic reticulum; Chemistry; Plasma membrane Ca2+ ATPase; Extracellular; Biophysics; Transmembrane protein; ATPase; Dithiothreitol; Transmembrane domain; Diaphragm pump; Calcium pump; Cysteine; Membrane; Peptide; Biochemistry; Enzyme; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000272757,0.0005608494,0.0007286185,0.0004005408,0.000424027,0.0005111882,0.0007263407,0.0005347112,0.001235579],"category_scores_gemma":[0.0002307372,0.0001777131,0.0003216818,0.0002227249,0.0003085539,0.0003155274,0.0002678227,0.0009444926,0.0003523654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008411165,"about_ca_system_score_gemma":0.0006889648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007661405,"about_ca_topic_score_gemma":0.001498344,"domain_scores_codex":[0.9998851,0.00001220142,0.000007321788,0.00002860391,0.00003249257,0.00003425416],"domain_scores_gemma":[0.9999137,0.00001409985,0.00001749616,0.000007103196,0.00001567962,0.00003185663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009059145,0.000205949,0.0003954688,0.00018489,0.00004906228,0.0003767895,0.00002305627,0.000325847,0.9775699,0.00111979,0.0009844539,0.0178588],"study_design_scores_gemma":[0.000871162,0.001966746,0.003538929,0.00002783316,0.0001665087,0.002426219,0.00002740578,0.003831686,0.9606735,0.0004113104,0.02603051,0.0000280999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9262437,0.02397265,0.03377177,0.002333886,0.000982652,0.0005691836,0.000724962,0.001272509,0.01012861],"genre_scores_gemma":[0.9713249,0.007307365,0.012524,0.000628477,0.0001441806,0.0002180713,0.001095724,0.00005804039,0.006699274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001235579,"threshold_uncertainty_score":0.006102741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698615798206629,"score_gpt":0.2649485032759573,"score_spread":0.247962345293891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}