{"id":"W2102843879","doi":"","title":"Targeting Cancer Stem Cells with Defined Compounds and Drugs","year":2013,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer stem cell; Sulforaphane; Parthenolide; Chemosensitizer; Cancer research; Cancer; Cancer cell; Curcumin; Cetuximab; Pharmacology; Metastasis; Medicine; Chemistry; In vitro; Colorectal cancer; Cytotoxicity; Internal medicine; Apoptosis; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001237417,0.0003791195,0.0002140124,0.0003299954,0.0001379595,0.0003542305,0.0002706254,0.0003352076,0.001200011],"category_scores_gemma":[0.00006146551,0.00008801356,0.0001770661,0.0002301645,0.0002006767,0.0002504479,0.0002072225,0.000449896,0.0005058055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005783602,"about_ca_system_score_gemma":0.0003702087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004653375,"about_ca_topic_score_gemma":0.0008192097,"domain_scores_codex":[0.999933,0.000009911058,0.000007194128,0.00001684126,0.00002106622,0.00001196249],"domain_scores_gemma":[0.9999694,0.000004162872,0.000008036782,0.00000341363,0.000007937124,0.000007134958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001780203,0.0001691939,0.0001665276,0.0002797174,0.0000162593,0.00008224962,0.00002767937,0.0005638622,0.9705518,0.002868672,0.0005602083,0.02453564],"study_design_scores_gemma":[0.00004905846,0.000471014,0.0003146694,0.00001461303,0.0000201391,0.00011037,0.00000814809,0.0007135976,0.9782407,0.0001863221,0.01986602,0.000005269274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8664461,0.03789516,0.06053103,0.001248099,0.0004940206,0.0009496342,0.001707815,0.0007250471,0.03000309],"genre_scores_gemma":[0.9388754,0.01483638,0.0323099,0.0004690581,0.00006221888,0.0004826262,0.001027817,0.00005808067,0.01187846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001200011,"threshold_uncertainty_score":0.004196286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01895430968532594,"score_gpt":0.3315660122698619,"score_spread":0.312611702584536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}