{"id":"W2102866204","doi":"10.1186/1465-9921-14-96","title":"Ceramides: a potential therapeutic target in pulmonary emphysema","year":2013,"lang":"en","type":"article","venue":"Respiratory Research","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Elastase; Ceramide; Lung; Bronchoalveolar lavage; Neutrophil elastase; Pancreatic elastase; Medicine; Chemistry; Pathology; Internal medicine; Inflammation; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001169213,0.0001420068,0.0001610095,0.0002200821,0.0001354954,0.00008519833,0.0003707428,0.000185259,0.0002825154],"category_scores_gemma":[0.0001256108,0.000130328,0.00008163721,0.0003257799,0.0001495695,0.00001313969,0.0001940418,0.0003341492,0.000213502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002373753,"about_ca_system_score_gemma":0.0001867471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001447969,"about_ca_topic_score_gemma":0.000008773259,"domain_scores_codex":[0.9977972,0.0004586682,0.0002485756,0.0004477154,0.0004239451,0.0006238847],"domain_scores_gemma":[0.9991165,0.00003019841,0.00003116859,0.0004680364,0.000211426,0.0001426549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005759824,0.00008963422,0.008363207,0.00002192299,0.00001607888,0.00002041108,0.00003992253,0.0001224078,0.9837955,0.00008239941,0.001018766,0.00637211],"study_design_scores_gemma":[0.001713902,0.0005451845,0.1292194,0.00006181982,0.000009185277,0.00002769202,0.0008509303,0.001912999,0.6502993,0.003520835,0.2111063,0.0007324202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902719,0.006331685,0.0001842605,0.0001188925,0.0001130898,0.0004070638,0.000003588836,0.00001367024,0.002555893],"genre_scores_gemma":[0.9978073,0.0001024384,0.0001074582,0.0004585273,0.0007067542,0.0001518451,0.00001521044,0.00003497165,0.000615444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3334963,"threshold_uncertainty_score":0.5314622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0492786225236313,"score_gpt":0.3423032818510975,"score_spread":0.2930246593274662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}