{"id":"W2102867860","doi":"10.1371/journal.pone.0033299","title":"Both TLR2 and TRIF Contribute to Interferon-β Production during Listeria Infection","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Irish Research Council for Science, Engineering and Technology; Irish Research Council; Institut National de la Recherche Agronomique; Institut National de la Santé et de la Recherche Médicale; Science Foundation Ireland; Howard Hughes Medical Institute","keywords":"TRIF; IRF3; TLR2; Biology; Listeria monocytogenes; Innate immune system; Microbiology; Peptidoglycan; Interferon; Immune system; Toll-like receptor; Immunology; Gene; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000330205,0.0004803771,0.0003275743,0.0002575129,0.0001723928,0.000341552,0.0001654267,0.0003919891,0.0007954676],"category_scores_gemma":[0.000210013,0.0002296218,0.0002748317,0.00008971851,0.0001908326,0.0002729841,0.0004246058,0.0006180415,0.0003599778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002168283,"about_ca_system_score_gemma":0.0001945386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001589389,"about_ca_topic_score_gemma":0.0001575983,"domain_scores_codex":[0.9997124,0.00005756752,0.00002337024,0.00003909456,0.00004842358,0.000119214],"domain_scores_gemma":[0.9998381,0.00001575157,0.00003954524,0.00001827252,0.00003178792,0.00005644265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003220821,0.00001453915,0.0008130475,0.00003042427,0.000002903884,0.00008725055,0.00002236051,0.00003078849,0.9976689,0.00004235763,0.00002957984,0.0009357766],"study_design_scores_gemma":[0.0001064936,0.0005977192,0.06562309,0.000052875,0.00007155331,0.001862359,0.0003221065,0.002759922,0.9244662,0.0004212566,0.003692951,0.00002353386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994301,0.001696119,0.002422769,0.0001171842,0.00002798735,0.00001704362,0.000160667,0.0000608869,0.001196364],"genre_scores_gemma":[0.9962946,0.0006531699,0.001553878,0.00007062905,0.00003059459,0.0000398735,0.0002843304,0.00001783275,0.001055133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007954676,"threshold_uncertainty_score":0.002661049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02572359208102618,"score_gpt":0.2239368697985723,"score_spread":0.1982132777175462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}